Laboratoire des Maladies Transmissibles et des Substances Biologiquement Actives, Faculte de Pharmacie, Monastir, Tunisia.
Nat Prod Res. 2010 May;24(9):789-96. doi: 10.1080/14786410802529190.
The chemical composition of the essential oils obtained by hydrodistillation from the flowers of Retama raetam (Forssk.) Webb cultivated in Tunisia was determined by GC and GC/MS analysis. A total of 50 components representing 98.58% of the oil were identified: nonanal (35.75%), alpha-humulene (29.29%), acetaldehyde (7.84%), linalool (5,62%), myrcene (3.38%), tridecanal (2.21%), beta-caryophyllene (1.79%), alpha-terpinyl acetate (1.46%), terpinolene (1.26%) and methyl anthranilate (1.06%) were found to be the major components. The oil was evaluated for antibacterial and antifungal activities using a microdilution assay against some bacteria and yeasts. The minimal inhibitory concentrations (MIC) of the essential oil varied between 0.625 and 5 mg mL(-1) and the minimum bactericidal concentrations (MBC) were superior to 5 mg mL(-1) of oil for most strains. The antioxidant potential of the essential oil was evaluated using the 2,2'-diphenyl-1-picrylhydrazyl free radical scavenging method. The essential oil possesses good antioxidant properties (IC(50) = 0.800 mg mL(-1)). The results may suggest that the flower oil of R. raetam possesses compounds with antibacterial, antifungal and antioxidant capacities, and thus the oil can be explored as a natural preservative ingredient in food and/or pharmaceutical preparations.
通过气相色谱和气相色谱-质谱联用分析,确定了在突尼斯种植的滨藜(Retama raetam(Forssk.)Webb)花用水蒸馏法获得的精油的化学成分。共鉴定出 50 种成分,占油的 98.58%:壬醛(35.75%)、α-葎草烯(29.29%)、乙醛(7.84%)、芳樟醇(5.62%)、月桂烯(3.38%)、十三醛(2.21%)、β-石竹烯(1.79%)、α-萜品醇乙酸酯(1.46%)、萜品烯(1.26%)和邻氨基苯甲酸甲酯(1.06%)被认为是主要成分。采用微量稀释法测定了该精油对一些细菌和酵母的抗菌和抗真菌活性。精油的最小抑菌浓度(MIC)在 0.625 至 5mg/mL 之间,大多数菌株的最小杀菌浓度(MBC)高于 5mg/mL 的油。采用 2,2'-二苯基-1-苦基肼自由基清除法评价了精油的抗氧化潜力。精油具有良好的抗氧化性能(IC50=0.800mg/mL)。结果表明,滨藜花油具有抗菌、抗真菌和抗氧化能力的化合物,因此该油可以作为天然防腐剂在食品和/或药物制剂中进行探索。