Yasuda Chieko, Ueno Shinji, Kondo Mineo, Kondo Nagako, Piao Chang-Hua, Terasaki Hiroko
Department of Ophthalmology, Nagoya University School of Medicine, Nagoya, Japan.
Clin Ophthalmol. 2010 Apr 26;4:301-6. doi: 10.2147/opth.s9618.
To follow the changes in the electroretinograms (ERGs) in a patient with primary intraocular lymphoma (PIOL) who had a complete remission after chemotherapy.
ERGs were recorded in a 41-year-old woman with PIOL during and after complete remission with chemotherapy. The patient was diagnosed with PIOL from both the ocular signs and the medical history of cranial lymphoma.
The ERGs were depressed in the subject. The amplitudes of the bright white flash b-waves were smaller than the a-waves, resulting in a "negative type" ERG. Six weeks after the beginning of chemotherapy, the ocular changes had resolved, and the ERGs, although not of the "negative type", still showed signs that the amplitude had not returned to normal levels.
The negative type ERGs indicated that the inner retina had been damaged to a greater extent than the outer retina. In the convalescent stage, when the ocular manifestations were resolved, the ERGs were still not fully recovered. Although only one case was studied, we suggest that ERGs can be used to evaluate and follow patients with a PIOL.
跟踪一名原发性眼内淋巴瘤（PIOL）患者化疗后完全缓解时视网膜电图（ERG）的变化。
对一名41岁患有PIOL的女性患者在化疗完全缓解期间及之后记录ERG。该患者根据眼部体征和颅内淋巴瘤病史被诊断为PIOL。
该受试者的ERG降低。明亮白色闪光b波的振幅小于a波，导致出现“阴性型”ERG。化疗开始六周后，眼部变化已消退，ERG虽不是“阴性型”，但仍显示振幅未恢复到正常水平的迹象。
阴性型ERG表明视网膜内层比外层受损程度更大。在恢复期，当眼部表现消退时，ERG仍未完全恢复。尽管仅研究了一例病例，但我们建议ERG可用于评估和跟踪PIOL患者。
