Mosqueira Carolina Balbi, Xavier Augusto Frederico de Paula, Tuschinski Cíntia Letícia, Pinto Clóvis A Lopes, Cunha Paulo R
Faculdade de Medicina de Jundiaí, SP, Brasil.
An Bras Dermatol. 2010 Jan-Feb;85(1):107-8. doi: 10.1590/s0365-05962010000100019.
Langerhans cell histiocytosis is a rare disease of unknown cause, characterized by the proliferation of histiocytic cells (Langerhans cells). Its diagnosis is especially difficult due to its wide clinical spectrum, ranging from a single lesion to a multisystemic disorder. Diagnosis may be confirmed by means of an immunohistochemical study. Treatment depends upon the severity of the disease, and systemic chemotherapy may be needed.
朗格汉斯细胞组织细胞增多症是一种病因不明的罕见疾病，其特征为组织细胞（朗格汉斯细胞）增殖。由于其临床谱广泛，从单一病灶到多系统疾病，其诊断尤为困难。诊断可通过免疫组织化学研究来证实。治疗取决于疾病的严重程度，可能需要全身化疗。
