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[作为动脉粥样硬化遗传易感性加重的青少年缺血性心脏病发生风险因素的中心血流动力学变化]

[Changes in central hemodynamics as a risk factor of the development of ischemic heart disease in adolescents with aggravated heredity of atherosclerosis].

作者信息

Belokon' N A, Leont'eva I V, Sipiagina A E, Aĭngorn E D, Metel'skaia V A

出版信息

Pediatriia. 1991(3):28-33.

PMID:2047176
Abstract

The authors provide the data on the central hemodynamics, blood plasma lipoproteins and apoproteins in 101 adolescents with aggravated heredity as regards coronary heart disease and in healthy adolescents of the same age serving as control. The hypokinetic variant of circulation is demonstrated to be coupled with the atherogenic nature of the lipoprotein and apoprotein spectra and heredity to contribute greatly to the traits under study. Criteria for the adolescents' inclusion into the group at the highest risk for early development of atherosclerosis are described.

摘要

作者提供了101名冠心病遗传易感性增强的青少年以及作为对照的同龄健康青少年的中心血流动力学、血浆脂蛋白和载脂蛋白的数据。结果表明,低动力循环变异与脂蛋白和载脂蛋白谱的致动脉粥样硬化性质相关,并且遗传对所研究的特征有很大影响。文中描述了将青少年纳入动脉粥样硬化早期发展最高风险组的标准。

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