End-of-Life Care Research Group, Vrije Universiteit Brussel, Brussels, Belgium.
CMAJ. 2010 Jun 15;182(9):895-901. doi: 10.1503/cmaj.091876. Epub 2010 May 17.
Legalization of euthanasia and physician-assisted suicide has been heavily debated in many countries. To help inform this debate, we describe the practices of euthanasia and assisted suicide, and the use of life-ending drugs without an explicit request from the patient, in Flanders, Belgium, where euthanasia is legal.
We mailed a questionnaire regarding the use of life-ending drugs with or without explicit patient request to physicians who certified a representative sample (n = 6927) of death certificates of patients who died in Flanders between June and November 2007.
The response rate was 58.4%. Overall, 208 deaths involving the use of life-ending drugs were reported: 142 (weighted prevalence 2.0%) were with an explicit patient request (euthanasia or assisted suicide) and 66 (weighted prevalence 1.8%) were without an explicit request. Euthanasia and assisted suicide mostly involved patients less than 80 years of age, those with cancer and those dying at home. Use of life-ending drugs without an explicit request mostly involved patients 80 years of older, those with a disease other than cancer and those in hospital. Of the deaths without an explicit request, the decision was not discussed with the patient in 77.9% of cases. Compared with assisted deaths with the patient's explicit request, those without an explicit request were more likely to have a shorter length of treatment of the terminal illness, to have cure as a goal of treatment in the last week, to have a shorter estimated time by which life was shortened and to involve the administration of opioids.
Physician-assisted deaths with an explicit patient request (euthanasia and assisted suicide) and without an explicit request occurred in different patient groups and under different circumstances. Cases without an explicit request often involved patients whose diseases had unpredictable end-of-life trajectories. Although opioids were used in most of these cases, misconceptions seem to persist about their actual life-shortening effects.
安乐死和医师协助自杀的合法化在许多国家都备受争议。为了帮助推动这场辩论,我们描述了在比利时佛兰德斯地区安乐死合法化的情况下,实施安乐死和协助自杀的情况,以及在没有患者明确要求的情况下使用致死药物的情况。
我们向在 2007 年 6 月至 11 月期间,为佛兰德斯地区的死亡证明上的患者进行认证的医生,邮寄了一份关于使用或不使用明确患者请求的致死药物的调查问卷。
回复率为 58.4%。总体而言,报告了 208 例涉及使用致死药物的死亡案例:142 例(加权患病率 2.0%)是在明确患者请求下(安乐死或协助自杀)进行的,66 例(加权患病率 1.8%)是在没有明确请求下进行的。安乐死和协助自杀主要涉及年龄小于 80 岁、患有癌症且在家中死亡的患者。在没有明确请求的情况下使用致死药物的案例主要涉及年龄大于 80 岁、患有非癌症疾病且在医院的患者。在没有明确请求的情况下,77.9%的案例没有与患者讨论过这个决定。与有患者明确请求的协助死亡相比,没有明确请求的案例更有可能是患者的疾病的治疗时间更短、最后一周的治疗目标是治愈、预计缩短生命的时间更短,且更有可能使用阿片类药物。
有明确患者请求(安乐死和协助自杀)和没有明确请求的医师协助死亡发生在不同的患者群体和不同的情况下。没有明确请求的案例通常涉及疾病的临终轨迹不可预测的患者。尽管这些情况下通常使用阿片类药物,但人们似乎仍然对它们实际缩短生命的效果存在误解。