Department of Neurological Sciences, Fondazione IRCCS Ospedale Maggiore Policlinico, Centro Dino Ferrari, Università di Milano, Italy.
Int J Mol Sci. 2010 Mar 12;11(3):1070-81. doi: 10.3390/ijms11031070.
Advances in stem cell research have provided important understanding of the cell biology and offered great promise for developing new strategies for tissue regeneration. The beneficial effects of stem cell therapy depend also by the development of new approachs for the track of stem cells in living subjects over time after transplantation. Recent developments in the use of nanotechnologies have contributed to advance of the high-resolution in vivo imaging methods, including positron emission tomography (PET), single-photon emission tomography (SPECT), magnetic resonance (MR) imaging, and X-Ray computed microtomography (microCT). This review examines the use of nanotechnologies for stem cell tracking.
干细胞研究的进展为细胞生物学提供了重要的认识,并为开发组织再生的新策略提供了巨大的希望。干细胞治疗的有益效果还取决于在移植后随时间推移在活体中追踪干细胞的新方法的发展。纳米技术的最新进展有助于提高体内高分辨率成像方法的水平,包括正电子发射断层扫描(PET)、单光子发射断层扫描(SPECT)、磁共振(MR)成像和 X 射线计算机微断层扫描(microCT)。本综述考察了纳米技术在干细胞追踪中的应用。