Institute of Public Health, Madrid Health (Madrid Salud), Madrid City Council (Ayuntamiento de Madrid), Calle Juan Esplandiu, 11, 28007 Madrid, Spain.
Diabetes Metab. 2010 Sep;36(4):305-11. doi: 10.1016/j.diabet.2010.02.003. Epub 2010 May 18.
The study aimed to compare the self-perception of health, physiological distress and health-related quality of life (HRQL) in subjects with and without diabetes residing in a large metropolitan area (the city of Madrid), and to identify the variables associated with the poorest HRQL among diabetes patients.
In this case-control epidemiological study, we selected 358 patients with diabetes from the Madrid City Health Survey. For every patient, two controls without diabetes were randomly selected from the same database and matched for age, gender and health district. The resultant study population comprised 1074 subjects, who were analyzed according to their self-rated health status, with mental health assessed by the 12-item General Health Questionnaire (GHQ-12) and HRQL by the COOP/WONCA questionnaire. Independent variables included sociodemographic characteristics, lifestyle variables, associated chronic diseases and consumption of medications. Multivariate analyses were conducted using ANCOVA tests.
The prevalence of health perceived as fair or poor was 64.12% in those with diabetes vs 38.57% in those without diabetes (P<0.05). The GHQ-12 results showed that mental health was also significantly worse among diabetes sufferers, and the COOP/WONCA questionnaire results indicated significantly poorer HRQL in those with diabetes. The variables that determined a poorer perception of HRQL among diabetes sufferers were female gender, older age, obesity, lack of physical exercise, coexistence of depression, use of sleeping pills, and Alzheimer's and cerebrovascular diseases.
Self-rated health and psychological well-being, and HRQL, are all considerably poorer among patients with diabetes vs those without diabetes. The poorest quality of life among those with diabetes associated with female gender, depression, lack of exercise and obesity.
本研究旨在比较居住在大都市(马德里市)的糖尿病患者和非糖尿病患者的健康自我感知、生理痛苦和健康相关生活质量(HRQL),并确定与糖尿病患者最差 HRQL 相关的变量。
在这项病例对照的流行病学研究中,我们从马德里市健康调查中选择了 358 名糖尿病患者。对于每一位患者,我们从同一数据库中随机选择了两名没有糖尿病的对照者,并按年龄、性别和卫生区进行匹配。最终的研究人群包括 1074 名受试者,根据他们的自我健康状况进行分析,使用 12 项一般健康问卷(GHQ-12)评估心理健康,使用 COOP/WONCA 问卷评估 HRQL。自变量包括社会人口统计学特征、生活方式变量、相关慢性疾病和药物使用。使用方差分析(ANCOVA)测试进行多变量分析。
糖尿病患者中自认为健康状况不佳或较差的比例为 64.12%,而非糖尿病患者中为 38.57%(P<0.05)。GHQ-12 结果表明,糖尿病患者的心理健康状况也明显较差,而 COOP/WONCA 问卷结果表明,糖尿病患者的 HRQL 明显较差。确定糖尿病患者 HRQL 较差的变量是女性、年龄较大、肥胖、缺乏体育锻炼、抑郁共存、使用安眠药以及阿尔茨海默病和脑血管疾病。
与非糖尿病患者相比,糖尿病患者的自我健康感知和心理健康以及 HRQL 都明显较差。糖尿病患者中与女性、抑郁、缺乏运动和肥胖相关的生活质量最差。