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Lancet Oncol. 2008 Aug;9(8):721-9. doi: 10.1016/S1470-2045(08)70194-3.
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Ann Oncol. 2007 Sep;18(9):1554-60. doi: 10.1093/annonc/mdm194. Epub 2007 Aug 13.
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Up-to-date monitoring of childhood cancer long-term survival in Europe: leukaemias and lymphomas.欧洲儿童癌症长期生存的最新监测：白血病和淋巴瘤
Ann Oncol. 2007 Sep;18(9):1569-77. doi: 10.1093/annonc/mdm187. Epub 2007 Jul 28.
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Up-to-date and precise estimates of cancer patient survival: model-based period analysis.癌症患者生存的最新精准估计：基于模型的时期分析。
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Ethnicity and survival in childhood acute myeloid leukemia: a report from the Children's Oncology Group.儿童急性髓系白血病中的种族与生存情况：来自儿童肿瘤协作组的报告
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儿童白血病和淋巴瘤生存的地理和种族差异：美国菲律宾居民、亚裔美国人和白种人之间的比较。

Geographic and ethnic differences in childhood leukaemia and lymphoma survival: comparisons of Philippine residents, Asian Americans and Caucasians in the United States.

机构信息

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, Heidelberg D-69115, Germany.

出版信息

Br J Cancer. 2010 Jun 29;103(1):149-54. doi: 10.1038/sj.bjc.6605703. Epub 2010 May 18.

DOI:10.1038/sj.bjc.6605703
PMID:20485290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2905294/
Abstract

BACKGROUND

Childhood cancer survival estimates from developing nations are rare.

METHODS

Using the US SEER and the Manila and Rizal Cancer Registry databases in the Philippines, 5-year survival for childhood leukaemia and lymphoma in 2001-2005 among Asian Americans were compared with both Filipinos and Caucasians in the United States. Estimates for patients in the United States in earlier time periods were compared with that of Philippine residents to estimate delay in achievements of comparable levels of survival.

RESULTS

Childhood leukaemia and lymphoma relative survival was much lower in Filipinos living in the Philippines (32.9 and 47.7%) than in Asian Americans (80.1 and 90.5%) and Caucasians (81.9 and 87%). Achievement of comparable survival rates of Philippine residents lagged behind by 20 to >30 years compared with patients in the United States.

CONCLUSIONS

The large differences in survival estimates of US populations and Philippine residents highlight the deficiencies of paediatric cancer care delivery in the Philippines. The long survival lag underlines the need for major improvements in access to diagnostic and treatment facilities.

摘要

背景

发展中国家儿童癌症的生存估计数据较为罕见。

方法

利用美国 SEER 和菲律宾马尼拉及黎刹癌症登记处数据库，比较了 2001-2005 年期间在美国的亚裔美国人、菲律宾人和白种人儿童白血病和淋巴瘤的 5 年生存率。将美国不同时期患者的生存率与菲律宾居民的生存率进行了比较，以评估在实现类似生存水平方面的滞后情况。

结果

在菲律宾的菲律宾人（白血病为 32.9%，淋巴瘤为 47.7%）儿童白血病和淋巴瘤的相对生存率明显低于亚裔美国人（白血病为 80.1%，淋巴瘤为 90.5%）和白种人（白血病为 81.9%，淋巴瘤为 87%）。与美国的患者相比，菲律宾居民实现类似生存率的时间滞后了 20 至 30 年以上。

结论

美国人群和菲律宾居民生存率估计值的巨大差异突显了菲律宾儿童癌症治疗服务的不足。如此长的生存滞后突出表明，需要在获得诊断和治疗设施方面取得重大改善。