Division of Global Health Equity, Brigham and Women's Hospital and MGH Institute of Health Professions, Boston, MA 02120, USA.
Nurs Health Sci. 2010 Mar;12(1):119-26. doi: 10.1111/j.1442-2018.2009.00505.x.
As part of a larger randomized controlled trial examining the efficacy of an HIV/AIDS symptom management manual (n = 775), this study examined the prevalence of peripheral neuropathy in HIV-infected individuals at 12 sites in the USA, Puerto Rico, and Africa. Neuropathy was reported by 44% of the sample; however, only 29.4% reported initiating self-care behaviors to address the neuropathy symptoms. Antiretroviral therapy was found to increase the frequency of neuropathy symptoms, with an increased mean intensity of 28%. A principal axis factor analysis with Promax rotation was used to assess the relationships in the frequency of use of the 18 self-care activities for neuropathy, revealing three distinct factors: (i) an interactive self-care factor; (ii) a complementary medicine factor; and (iii) a third factor consisting of the negative health items of smoking, alcohol, and street drugs. The study's results suggest that peripheral neuropathy is a common symptom and the presence of neuropathy is associated with self-care behaviors to ameliorate HIV symptoms. The implications for nursing practice include the assessment and evaluation of nursing interventions related to management strategies for neuropathy.
作为一项更大规模的随机对照试验的一部分,该试验旨在研究一种艾滋病毒/艾滋病症状管理手册的疗效(n = 775),本研究在美国、波多黎各和非洲的 12 个地点调查了艾滋病毒感染者周围神经病变的患病率。该样本中有 44%的人报告患有周围神经病变;然而,只有 29.4%的人报告开始采取自我护理行为来解决神经病变症状。抗逆转录病毒疗法被发现会增加神经病变症状的频率,其平均强度增加了 28%。采用 Promax 旋转的主成分因子分析来评估 18 种用于神经病变的自我护理活动的使用频率之间的关系,揭示了三个不同的因素:(i)互动自我护理因素;(ii)补充医学因素;(iii)由吸烟、酒精和街头毒品等负面健康因素组成的第三个因素。该研究的结果表明,周围神经病变是一种常见症状,周围神经病变的存在与自我护理行为有关,可改善艾滋病毒症状。对护理实践的启示包括评估和评估与神经病变管理策略相关的护理干预措施。