Patel Shelain, Hossain Fahad S, Paton Bruce, Haddad Fares S
Department of Trauma and Orthopaedics, University College Hospital, London, UK.
Ann R Coll Surg Engl. 2010 Sep;92(6):467-71. doi: 10.1308/rcsann.2010.92.6.467. Epub 2010 May 19.
The purpose of this study was to determine if a multimodal programme including physiotherapy and education could improve the symptoms of osteoarthritis of the knee across various severities of disease.
Seventy-two patients with osteoarthritis of the knee confirmed on radiographic evidence were referred over a 13-month period for a lower limb programme which consisted of 12 classes over 6 weeks of group physiotherapy and included education on osteoarthritis, diet and exercise. Six patients went on to have joint arthroplasty at a mean time of 6.5 months with three placed on the waiting list during follow-up.
Pre-intervention, the mean WOMAC score was 42.0 and the mean Oxford Knee Score was 32.8. Post-intervention at a mean follow-up of 12 months, the mean WOMAC score was 31.6 and the mean Oxford Knee Score 24.3. The change in scores following intervention was statistically significant (P < 0.01). Using the WOMAC scoring system, the greatest effect size was seen in patients with Kellgren-Lawrence grade IV whilst using the Oxford knee scoring system, the greatest effect size was seen in patients with Kellgren-Lawrence grade II.
At 12 months, a multimodal programme of non-operative interventions has an excellent impact upon the symptoms of osteoarthritis of the knee with improved patient-reported scores. The level of improvement cannot be inferred from the radiographic grade of osteoarthritis. This modality could be considered for all patients with mild-to-moderate osteoarthritis of the knee.
本研究的目的是确定一个包括物理治疗和教育的多模式方案是否能改善不同疾病严重程度的膝关节骨关节炎症状。
72例经影像学证据确诊为膝关节骨关节炎的患者在13个月的时间里被转诊接受一项下肢方案,该方案包括6周内12节小组物理治疗课程,并包括有关骨关节炎、饮食和运动的教育。6例患者在平均6.5个月时接受了关节置换术,3例在随访期间被列入等待名单。
干预前,WOMAC平均评分为42.0,牛津膝关节评分为32.8。干预后平均随访12个月时,WOMAC平均评分为31.6,牛津膝关节评分为24.3。干预后评分变化具有统计学意义(P<0.01)。使用WOMAC评分系统,在Kellgren-Lawrence IV级患者中观察到最大效应量,而使用牛津膝关节评分系统,在Kellgren-Lawrence II级患者中观察到最大效应量。
在12个月时,非手术干预的多模式方案对膝关节骨关节炎症状有显著影响,患者报告的评分有所改善。改善程度不能从骨关节炎的影像学分级推断。对于所有轻至中度膝关节骨关节炎患者,可考虑采用这种治疗方式。