Department of Ophthalmology, Singapore National Eye Center, Singapore, Singapore.
Eye (Lond). 2010 Sep;24(9):1486-91. doi: 10.1038/eye.2010.67. Epub 2010 May 21.
To examine the impact of symptomatic dry eye on vision-related daily activities.
A population-based survey of eye diseases was conducted on 3280 (78.7% response rate) Malay persons aged >or=40 years, who were randomly selected from designated areas in southwestern Singapore. Participants were administered a standardized dry eye questionnaire consisting of six questions on symptoms, a questionnaire on vision-related daily activities, and underwent a comprehensive systemic and ocular examination. Symptomatic dry eye was defined as one or more self-reported symptoms that were frequently present (ranked as often or all the time). Logistic regression method was used to examine the relationship of symptomatic dry eye with difficulty in performing daily activities.
In adults without visual impairment, symptomatic dry eye after adjusting for age, gender, and presenting visual acuity was significantly associated with difficulty in vision-related activities such as navigating stairs (odds ratio (OR)=1.96, 95% confidence interval (CI): 1.28-3.00), recognizing friends (OR=1.99, 95% CI: 1.45-2.73), reading road signs (OR=1.87, 95% CI: 1.36-2.57), reading newspaper (OR=1.50, 95% CI: 1.11-2.04), watching television (OR=1.90, 95% CI: 1.26-2.87), cooking (OR=1.94, 95% CI: 1.02-3.71), and driving at night (OR=2.06, 95% CI: 1.32-3.21).
Symptomatic dry eye was associated with difficulty in performing vision-dependent tasks, independent of visual acuity and other factors. These findings have public health significance and suggest that the visual dysfunction in dry eye should be further characterized.
探讨症状性干眼对与视觉相关的日常活动的影响。
对 3280 名（78.7%应答率）年龄≥40 岁的马来人进行了基于人群的眼病调查，这些人是从新加坡西南部指定地区随机选择的。参与者接受了标准化的干眼问卷，包括 6 个关于症状的问题、一个与视觉相关的日常活动问卷，并进行了全面的系统和眼部检查。症状性干眼定义为存在一种或多种经常出现（评为经常或一直存在）的自我报告症状。使用逻辑回归方法检查症状性干眼与日常活动困难之间的关系。
在没有视力障碍的成年人中，调整年龄、性别和表现视力后，症状性干眼与视觉相关活动的困难显著相关，如上下楼梯（比值比（OR）=1.96，95%置信区间（CI）：1.28-3.00）、辨认朋友（OR=1.99，95%CI：1.45-2.73）、阅读路标（OR=1.87，95%CI：1.36-2.57）、阅读报纸（OR=1.50，95%CI：1.11-2.04）、看电视（OR=1.90，95%CI：1.26-2.87）、烹饪（OR=1.94，95%CI：1.02-3.71）和夜间驾驶（OR=2.06，95%CI：1.32-3.21）。
症状性干眼与依赖视觉的任务执行困难有关，独立于视力和其他因素。这些发现具有公共卫生意义，表明干眼的视觉功能障碍应进一步进行特征描述。
