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热力学原理在系统生物学中的影响。

Impact of thermodynamic principles in systems biology.

机构信息

Department Biotechnology, Bioprocess technology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands,

出版信息

Adv Biochem Eng Biotechnol. 2010;121:139-62. doi: 10.1007/10_2009_63.

DOI:10.1007/10_2009_63
PMID:20490971
Abstract

It is shown that properties of biological systems which are relevant for systems biology motivated mathematical modelling are strongly shaped by general thermodynamic principles such as osmotic limit, Gibbs energy dissipation, near equilibria and thermodynamic driving force. Each of these aspects will be demonstrated both theoretically and experimentally.

摘要

研究表明,与系统生物学相关的生物系统特性强烈地受到一般热力学原理的影响,如渗透极限、吉布斯能耗散、近平衡和热力学驱动力。这些方面都将从理论和实验两个方面进行论证。

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