Duportets L, Barrozo R B, Bozzolan F, Gaertner C, Anton S, Gadenne C, Debernard S
UMR 1272, UPMC-INRA, Physiologie de l'Insecte: Signalisation et Communication, Université Paris VI, Bât A, 7 quai Saint Bernard, Paris, France.
Insect Mol Biol. 2010 Aug;19(4):489-99. doi: 10.1111/j.1365-2583.2010.01009.x. Epub 2010 May 20.
In the male moth Agrotis ipsilon behavioural response and antennal lobe (AL) neuron sensitivity to the female-produced sex pheromone increase with age and juvenile hormone (JH) level. We recently showed that the neuromodulator, octopamine (OA), interacts with JH in this age-dependent olfactory plasticity. To further elucidate its role, we cloned a full cDNA encoding a protein that presents biochemical features essential to OA/tyramine receptor (AipsOAR/TAR) function. The AipsOAR/TAR transcript was detected predominantly in the antennae, the brain and, more specifically, in ALs where its expression level varied concomitantly with age. This expression plasticity indicates that AipsOAR/TAR might be involved in central processing of the pheromone signal during maturation of sexual behaviour in A. ipsilon.
在雄性小地老虎蛾中，其行为反应以及触角叶（AL）神经元对雌性产生的性信息素的敏感性会随着年龄和保幼激素（JH）水平的升高而增强。我们最近发现，神经调质章鱼胺（OA）在这种年龄依赖性嗅觉可塑性中与JH相互作用。为了进一步阐明其作用，我们克隆了一个完整的cDNA，该cDNA编码一种具有OA/酪胺受体（AipsOAR/TAR）功能所必需生化特征的蛋白质。AipsOAR/TAR转录本主要在触角、大脑中检测到，更具体地说，在触角叶中检测到，其表达水平随年龄而变化。这种表达可塑性表明，AipsOAR/TAR可能参与了小地老虎蛾性行为成熟过程中信息素信号的中枢处理。
