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红细胞沉降率缩短评估适用于住院患者。

Shortened erythrocyte sedimentation rate evaluation is applicable to hospitalised patients.

机构信息

Department of Internal Medicine F, Assaf Harofeh Medical Center (affiliated to Sackler School of Medicine, Tel-Aviv University), Zerifin, Israel.

出版信息

Eur J Intern Med. 2010 Jun;21(3):226-9. doi: 10.1016/j.ejim.2010.02.002. Epub 2010 Feb 25.

Abstract

BACKGROUND

Westergren method, commonly used for erythrocyte sedimentation rate (ESR) determination, is simple and inexpensive. However, the 60 min required for the test are disadvantageous, especially for those departments/facilities where prompt evaluation is necessary. We investigated the possibility that earlier ESR recordings might correlate with standard 60-minute ESR and/or be predictive of the latter.

METHODS

Demographic and clinical data were collected from 220 randomly chosen adult patients hospitalised for various diseases in a medical department. ESR, determined by slightly modified Westergren method, was recorded at 15, 30 and 60 min. Correlation coefficients (r) between the standard and early ESR measurements were calculated for the entire group and for the separate subgroups divided according to patient age, sex and presence of anaemia or of inflammation.

RESULTS

Mean+/-SD age of the patients was 61.3+/-19.6, 55% were males; 45% had some inflammatory condition. Mean+/-SD ESR values (mm) at 15, 30 and 60 min were 9.0+/-12.1, 21.4+/-21.8 and 35.9+/-27.5, respectively. A statistically significant correlation was found between ESR measurements at 15 and 60 min (r=0.833, p<0.001). However, the strongest correlation was observed between 30 and 60 min measurements (r=0.926, p<0.001), irrespective of age, sex and presence of anaemia or of inflammation. Based on the ESR determination at 30 min (X), the predicted ESR value at 60 min (Y) could be calculated by a simple equation: Y=10.7+1.2X.

CONCLUSION

Sixty-minute ESR values can be predicted by the 30-minute estimation. Shortening the test by half an hour might bear practical importance.

摘要

背景

魏氏血沉法(Westergren method)常用于红细胞沉降率(erythrocyte sedimentation rate,ESR)的测定,其操作简单且费用低廉。但该方法耗时 60 分钟,对于需要快速评估的科室/设施来说较为不利。我们研究了早期血沉记录是否与标准 60 分钟血沉相关,或者是否能预测后者。

方法

从某医学科随机选取 220 名住院的成年患者,收集其人口统计学和临床数据。采用改良魏氏血沉法,在 15 分钟、30 分钟和 60 分钟时记录血沉。计算整个组和根据患者年龄、性别以及是否存在贫血或炎症进行分组的亚组中,标准血沉测量值与早期血沉测量值之间的相关系数(r)。

结果

患者的平均年龄+/-标准差为 61.3+/-19.6 岁,55%为男性;45%存在某种炎症情况。15 分钟、30 分钟和 60 分钟时的平均血沉值(mm)分别为 9.0+/-12.1、21.4+/-21.8 和 35.9+/-27.5。15 分钟和 60 分钟时的血沉测量值之间存在统计学显著相关性(r=0.833,p<0.001)。然而,30 分钟和 60 分钟时的测量值之间的相关性最强(r=0.926,p<0.001),无论年龄、性别以及是否存在贫血或炎症。根据 30 分钟时的血沉测定值(X),可通过简单方程计算 60 分钟时的预测血沉值(Y):Y=10.7+1.2X。

结论

60 分钟的血沉值可以通过 30 分钟的估计来预测。将测试时间缩短半小时可能具有实际意义。

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