Blanchard M, Méneret A, Moguelet P, Brian E, Baron M, Khosrotehrani K, Bazelly B, Bachmeyer C
Service de médecine interne, CHU Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France.
Rev Med Interne. 2010 Jul;31(7):498-501. doi: 10.1016/j.revmed.2009.12.010. Epub 2010 May 21.
Good syndrome is characterized by thymoma, hypogammaglobulinemia, low number of peripheral B cells, and variably, peripheral CD4 T cell lymphopenia and inverted CD4/CD8 T cell ratio, associated with infections and autoimmune diseases.
We report an 85-year-old woman who presented with oral erosive lichen planus and thymic tumor. Improvement of oral erosive lichen planus was observed after resection of a benign thymoma, but was ineffective on the immunodeficiency syndrome. Only 11 patients with Good syndrome and lichen planus have been previously reported and are reviewed.
The association of oral erosive lichen planus with Good syndrome is rare, but does not seem to be fortuitous.