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基于 Kaplan-Baycrest 神经认知评估的轻度痴呆诊断预测。

The diagnostic prediction of the Kaplan-Baycrest neurocognitive assessment for identification of mild dementia.

机构信息

Cognitive & Behavioural Health Program - Psychology, Baycrest Geriatric Health Care System, Toronto, Ontario, Canada.

出版信息

Arch Clin Neuropsychol. 2010 Aug;25(5):359-70. doi: 10.1093/arclin/acq034. Epub 2010 May 25.

DOI:10.1093/arclin/acq034
PMID:20501507
Abstract

The purpose of this study was to: (1) determine the diagnostic prediction of the global score of the Kaplan-Baycrest Neurocognitive Assessment and (2) determine which subtests discriminate individuals with mild dementia from individuals without dementia. A case-control study of 33 individuals, diagnosed with mild dementia, was matched with 33 individuals with no cognitive or memory complaints, on age, education, and gender. A global measure score correctly classified 94% of the total sample with a sensitivity of 0.91 and specificity of 0.97. A measure composed of three subtest scores, representing verbal episodic memory, visual episodic memory, and semantic fluency, correctly classified 98% of the sample with a sensitivity of 1.00 and specificity of 0.97. The results indicate that the Kaplan-Baycrest Neurocognitive Assessment is a valid tool for prediction of cognitive impairment associated with mild dementia.

摘要

本研究旨在

(1) 确定 Kaplan-Baycrest 神经认知评估的全球评分的诊断预测能力,(2) 确定哪些子测验可以区分轻度痴呆患者和无痴呆患者。一项病例对照研究纳入了 33 名被诊断为轻度痴呆的患者,并与 33 名无认知或记忆主诉的患者进行了匹配,匹配因素包括年龄、教育程度和性别。全球评分量表正确分类了 94%的总样本,敏感性为 0.91,特异性为 0.97。由三个子测验分数组成的测量指标,分别代表语言情景记忆、视觉情景记忆和语义流畅性,正确分类了 98%的样本,敏感性为 1.00,特异性为 0.97。结果表明,Kaplan-Baycrest 神经认知评估是一种预测与轻度痴呆相关的认知障碍的有效工具。

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