Donald F E, Slack R C, Colman G
Department of Microbiology, University Hospital, Queen's Medical Centre, Nottingham.
Epidemiol Infect. 1991 Jun;106(3):459-65. doi: 10.1017/s0950268800067509.
Isolates of Streptococcus pyogenes from vaginal swabs of children with vulvovaginitis received at Nottingham Public Health Laboratory during 1986-9 were studied. A total of 159 isolates was made during the 4 years, increasing from 17 in 1986 to 64 in 1989 and accounting for 11% of all vaginal swabs received from children. The numbers of throat swabs yielding S. pyogenes also showed an increase from 974 in 1986 to 1519 in 1989. A winter peak of isolates was noted for both vaginal swabs and throat swabs. A total of 98 strains from vaginal swabs were serotyped: 22 different types were identified, 61% of which were the common types M4, M6, R28 and M12. Erythromycin sensitivity was done on 89 strains; 84% were highly sensitive (MIC less than 0.03 mg/l). There are no other reports of such large numbers in the literature; the reason for seeing this increase in Nottingham is unclear.
对1986年至199年期间诺丁汉公共卫生实验室收到的患有外阴阴道炎儿童的阴道拭子中的化脓性链球菌分离株进行了研究。4年间共分离出159株，从1986年的17株增加到1989年的64株，占从儿童处收到的所有阴道拭子的11%。产生化脓性链球菌的咽拭子数量也从1986年的974株增加到1989年的1519株。阴道拭子和咽拭子的分离株均出现冬季高峰。对98株阴道拭子菌株进行了血清分型：鉴定出22种不同类型，其中61%为常见类型M4、M6、R28和M12。对89株菌株进行了红霉素敏感性检测；84%高度敏感（最低抑菌浓度小于0.03mg/l）。文献中没有其他如此大量的报道；诺丁汉出现这种增加的原因尚不清楚。
