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聚电解质复合物：其在药物递送技术中的适用性综述

Polyelectrolyte Complexes: A Review of their Applicability in Drug Delivery Technology.

作者信息

Lankalapalli S, Kolapalli V R M

机构信息

Raghu College of Pharmacy, Dakamarri, Bheemunipatnam, Visakhapatnam 531 162, India.

出版信息

Indian J Pharm Sci. 2009 Sep;71(5):481-7. doi: 10.4103/0250-474X.58165.

DOI:10.4103/0250-474X.58165
PMID:20502564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2866337/
Abstract

Over the past several years, great advances have been made towards novel drug delivery systems. The phenomena of interpolymer interactions and formation of polyelectrolyte complexes have been the focus of intensive fundamental and applied research. Interpolyelectrolyte complexes combine unique physicochemical properties with high biocompatibility. Studies have been carried out on many different polymer blends and types. Such combinations may possess unique properties that are different from those of individual component. The present review emphasizes on the applicability of polyelectrolyte complexes in drug delivery technology.

摘要

在过去几年中，新型药物递送系统取得了巨大进展。聚合物间相互作用和聚电解质复合物形成的现象一直是深入的基础研究和应用研究的重点。聚电解质复合物将独特的物理化学性质与高生物相容性结合在一起。已经对许多不同的聚合物共混物和类型进行了研究。这样的组合可能具有与单个组分不同的独特性质。本综述重点关注聚电解质复合物在药物递送技术中的适用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c13e/2866337/9cadf5c746ec/IJPhS-71-481-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c13e/2866337/9cadf5c746ec/IJPhS-71-481-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c13e/2866337/9cadf5c746ec/IJPhS-71-481-g001.jpg

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本文引用的文献

[1]
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[2]
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J Drug Target. 2003-4

[10]
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Anal Bioanal Chem. 2003-4

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