Smith G N, Taj M, Braganza J M
Department of Chemistry, University of Manchester, England.
Free Radic Biol Med. 1991;10(1):13-21. doi: 10.1016/0891-5849(91)90016-v.
The lipid free radical marker, termed diene conjugation, in secretin-stimulated human bile obtained from the duodenum, was shown by high performance liquid chromatography and capillary gas chromatography-mass spectrometry, to be due mainly to 9Z,11E-octadecadienoic acid. The lack of evidence for possible conjugated diene isomers argues for an enzymatic origin of this product rather than being due to a random free radical mechanism, as is usually assumed.
通过高效液相色谱法和毛细管气相色谱 - 质谱分析法显示，从十二指肠获取的促胰液素刺激的人胆汁中的脂质自由基标志物（称为二烯共轭）主要归因于9Z,11E - 十八碳二烯酸。缺乏可能的共轭二烯异构体的证据表明，该产物起源于酶促反应而非通常所认为的随机自由基机制。
