Riedel R R, Bader L, Naber D, Gürtler L, Günther W, Deinhardt F, Hippius H
Universitäts-Nervenklinik/Psychiatrie, LMU München.
Fortschr Neurol Psychiatr. 1991 Mar;59(3):69-80. doi: 10.1055/s-2007-1000681.
Since 1986 the notation Human Immunodeficiency Virus (HIV) is used for the retroviral agent of the Acquired Immunodeficiency Syndrome (AIDS). At the beginning of the therapeutical interest in the immunodeficiency syndrome have been primarily focussed in the internal complications. 1982 one reported for the first time about nervous system manifestations (NS-M) in HIV-patients; according to the latest reports NS-M are diagnosed in 39-63% of these patients. In this review all important aspects of the pathogenesis, clinic and therapy for the HIV-associated peripheric- and central-neurological (like e.g. acute and chronic meningitis/meningoencephalitis, dementia, opportunistic infections, polyneuropathies and myopathies) and psychiatric diseases are described.
自1986年起，“人类免疫缺陷病毒（HIV）”这一术语被用于指代获得性免疫缺陷综合征（AIDS）的逆转录病毒病原体。在对免疫缺陷综合征的治疗研究初期，主要关注的是其内部并发症。1982年，首次报道了HIV患者的神经系统表现（NS-M）；根据最新报告，这些患者中有39%至63%被诊断出患有NS-M。在这篇综述中，描述了HIV相关的外周和中枢神经疾病（如急性和慢性脑膜炎/脑膜脑炎、痴呆、机会性感染、多发性神经病和肌病）以及精神疾病在发病机制、临床和治疗方面的所有重要方面。
