Pascale C, Zampaglione B
Dipartimento di Emergenza, Ospedale Martini di Torino.
Minerva Cardioangiol. 1994 Apr;42(4):125-47.
Hypertensive crisis may be defined as a condition characterized by a sudden rise in blood pressure, of varying length, that can damage arteries, arteriolas, and capillary vessels, producing impairment of end-organs. Hypertensive crises may occur under different clinical conditions, for this reason it is necessary to classify them according to their clinical context. Hypertensive crises are generally classified as hypertensive emergencies or urgencies on the basis of the clinical evaluation and according to the level of blood pressure and the presence of acute or ongoing end-organ damage. Hypertensive emergencies are conditions characterized by a great rise in blood pressure in the presence of acute or ongoing end-organ damages. A severe elevation of blood pressure is considered an emergency if there is an evidence of rapid or progressive damage to the central nervous system and myocardial, or renal deterioration. These are situations in which greatly elevated blood pressure must be lowered within one hour in order to reduce actual risk for the patient. Hypertensive urgencies are conditions in which severe elevations in blood pressure do not cause immediate end-organ damages but should be controlled within 24 hours in order to reduce potential risk for the patient. This group includes accelerated hypertension, severe elevation of blood pressure with minimal end-organ damages and no impending complications. In order to formulate a correct therapeutic plan and make the best use of the powerful antihypertensive drugs at our disposal, it is therefore necessary to distinguish hypertensive emergencies from hypertensive urgencies.
高血压危象可定义为一种以血压突然升高为特征的病症,其持续时间各异,可损害动脉、小动脉和毛细血管,导致靶器官功能受损。高血压危象可在不同临床情况下发生,因此有必要根据其临床背景进行分类。根据临床评估以及血压水平和急性或持续性靶器官损害的情况,高血压危象通常分为高血压急症或亚急症。高血压急症是指在存在急性或持续性靶器官损害的情况下血压大幅升高的病症。如果有证据表明中枢神经系统、心肌或肾脏迅速或进行性受损,血压严重升高则被视为急症。在这些情况下,必须在一小时内将大幅升高的血压降低,以降低患者的实际风险。高血压亚急症是指血压严重升高但未立即导致靶器官损害,但应在24小时内得到控制以降低患者潜在风险的情况。这一组包括急进性高血压、血压严重升高但靶器官损害轻微且无即将发生的并发症。因此,为了制定正确的治疗方案并充分利用我们现有的强效降压药物,有必要区分高血压急症和高血压亚急症。