Campos Teresa Salas, Rodríguez-Santos Francisco, Esteban Jesus, Vázquez Pilar Cordero, Mora Pardina Jesus S, Carmona Alejandra Cano
ALS Unit Hospital Carlos III, Madrid, Spain.
Amyotroph Lateral Scler. 2010 Oct;11(5):475-7. doi: 10.3109/17482968.2010.489115.
ALSFRS-R is a tool designed to measure disease progress in ALS patients. It consists of 12 items grouped into four functions designed to assess disabilities according to the Activities of daily living (ADL). Our objective was to validate the Spanish version of ALSFRS-R based on the original version. Four examiners assessed 73 ALS patients, applying the ALSFRS-R, ALSAQ-40 and the respiratory function variable assessed by the SRI scale, which measures respiratory insufficiency. Internal consistency and test-retest correlations were measured using Cronbach's alpha and Spearman's Rho tests. Factor analysis was performed by applying Varimax rotation and Kaiser standardization. Validity was analysed based on correlations between items in the ALSFRS-R scales and equivalents in the ALSAQ-40 and SRI questionnaires. The results showed high internal consistency (0.77-0.95) and a good test-retest correlation (0.80-0.95). Factor analysis showed a 73.3% principal component contribution; the weight of each item regarding their corresponding factors was 0.7-0.9. High correlations were observed (rs >0.60) between corresponding factors of ALSFRS-R/ALSAQ-40 and ALSFRS-R/SRI. We conclude that the version obtained from the ALSFRS-R maintains the internal consistency and validity of the construct of the original scale. The Spanish version of ALSFRS-R is available for readers at http://www.fundela.es/verOtras.php.
肌萎缩侧索硬化功能评定量表修订版（ALSFRS-R）是一种用于测量肌萎缩侧索硬化症（ALS）患者疾病进展的工具。它由12个项目组成，分为四个功能类别，旨在根据日常生活活动（ADL）评估残疾情况。我们的目标是基于原始版本验证ALSFRS-R的西班牙语版本。四名检查人员对73名ALS患者进行了评估，应用了ALSFRS-R、ALS功能评定问卷（ALSAQ-40）以及通过SRI量表评估的呼吸功能变量，该量表用于测量呼吸功能不全。使用克朗巴哈系数（Cronbach's alpha）和斯皮尔曼等级相关系数（Spearman's Rho）检验来测量内部一致性和重测相关性。通过应用方差最大化旋转和凯泽标准化进行因子分析。基于ALSFRS-R量表中的项目与ALSAQ-40和SRI问卷中的等效项目之间的相关性分析有效性。结果显示出高内部一致性（0.77 - 0.95）和良好的重测相关性（0.80 - 0.95）。因子分析显示主成分贡献率为73.3%；每个项目相对于其相应因子的权重为0.7 - 0.9。在ALSFRS-R/ALSAQ-40和ALSFRS-R/SRI的相应因子之间观察到高相关性（rs >0.60）。我们得出结论，从ALSFRS-R获得的版本保持了原始量表结构的内部一致性和有效性。ALSFRS-R的西班牙语版本可在http://www.fundela.es/verOtras.php上供读者使用。
