Queiroz D M, Rocha G A, Mendes E N, Carvalho A S, Barbosa A J, Oliveira C A, Lima G F
Laboratory of Research in Bacteriology, Faculdade de Medicina, Universidade Federal de Minas Gerais, Minas Gerais, Brazil.
J Pediatr Gastroenterol Nutr. 1991 Feb;12(2):178-81. doi: 10.1097/00005176-199102000-00007.
The presence of Helicobacter pylori and the gastric mucosa histology were investigated in 15 children and 15 adults with duodenal ulcer. The microorganism was isolated from antral and oxyntic mucosa in 100% of patients, both adults and children. The results of Gram stain and preformed urease test were compared with those of culture and there was no difference in sensitivity among the tests. Antral chronic gastritis was observed in all patients. However, children presented oxyntic gastritis more frequently than adults. It was also observed that the endoscopic aspects were different in the two groups of patients. The results here observed strongly support the idea that, as well as in adults, H. pylori is the causative agent of the gastritis seen in children with duodenal ulceration. On the other hand, the histological findings of oxyntic mucosa of children with duodenal ulcer were different from those of adults.
对15名患有十二指肠溃疡的儿童和15名成人进行了幽门螺杆菌检测及胃黏膜组织学检查。在所有患者（包括成人和儿童）中，均从胃窦和胃体黏膜中分离出该微生物。将革兰氏染色和预先进行的尿素酶试验结果与培养结果进行比较，各检测方法的敏感性无差异。所有患者均观察到胃窦慢性胃炎。然而，儿童比成人更频繁地出现胃体胃炎。还观察到两组患者的内镜表现不同。此处观察到的结果有力地支持了这样一种观点，即与成人一样，幽门螺杆菌也是患有十二指肠溃疡的儿童胃炎的病原体。另一方面，患有十二指肠溃疡的儿童胃体黏膜的组织学发现与成人不同。
