Ng T H, How S H, Kuan Y C, Aziz A A, Fauzi A R
Department of Internal Medicine, Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan.
Malays J Pathol. 2009 Dec;31(2):147-50.
Klebsiella ozaenae is a Gram negative bacillus. It has been described as a colonizer of oral and nasopharyngeal mucosa and is a cause of atrophic rhinitis. Klebsiella ozaenae has seldom been isolated from serious infections. However, several reports have stated that Klebsiella ozaenae may cause invasive infections and even mortality. We report a 55-year-old man with Klebsiella ozaenae infection causing abscesses involving the right eye and left kidney and possibly also in the brain, lungs and prostate. The isolates were sensitive to ceftazidime, ciprofloxacin, chloramphenicol, gentamicin and sulfamethoxazole-trimethoprim but resistant to ampicillin. He responded well to 4 weeks of i.v. ceftazidime and i.v. amoxycillin-clavulanic acid. To our knowledge, such a multiorgan infection has not been reported previously for this organism.
臭鼻克雷伯菌是一种革兰氏阴性杆菌。它被描述为口腔和鼻咽黏膜的定植菌，是萎缩性鼻炎的病因。臭鼻克雷伯菌很少从严重感染中分离出来。然而，有几份报告指出，臭鼻克雷伯菌可能导致侵袭性感染甚至死亡。我们报告了一名55岁男性，感染臭鼻克雷伯菌，导致右眼和左肾脓肿，可能还累及脑、肺和前列腺。分离菌株对头孢他啶、环丙沙星、氯霉素、庆大霉素和复方磺胺甲恶唑敏感，但对氨苄西林耐药。他对静脉注射头孢他啶和静脉注射阿莫西林-克拉维酸治疗4周反应良好。据我们所知，此前尚未报道过该菌引起的这种多器官感染。
