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肯尼亚沿海地区人群中虫媒病毒感染的血清学证据。

Serological evidence of arboviral infections among humans of coastal Kenya.

作者信息

Morrill J C, Johnson B K, Hyams C, Okoth F, Tukei P M, Mugambi M, Woody J

机构信息

US Naval Medical Research Unit No. 3, Cairo, Arab Republic of Egypt.

出版信息

J Trop Med Hyg. 1991 Jun;94(3):166-8.

PMID:2051522
Abstract

A serosurvey was conducted during September 1987 for evidence of human arboviral infections in the Coast Province of Kenya. Sera were collected from 1624 outpatients at three hospitals and tested for antibody to eight arboviruses by the indirect immunofluorescent antibody technique. Antibody prevalence rates were: Rift Valley fever, 2.8%; Sindbis, 2.6%; dugbe, 2.1%; dengue-2, 1.0%; West Nile, 0.9%; chikungunya, 0.7% and Nairobi sheep disease, 0.3%. Evidence of Crimean-Congo haemorrhagic fever viral antibody was not detected. The data suggested low arbovirus activity since 1982, when an epidemic of dengue occurred in this region, and revealed the first evidence of dugbe viral infection among humans in Kenya.

摘要

1987年9月在肯尼亚沿海省进行了一项血清学调查,以寻找人类虫媒病毒感染的证据。从三家医院的1624名门诊病人中采集血清,并用间接免疫荧光抗体技术检测了针对八种虫媒病毒的抗体。抗体流行率分别为:裂谷热2.8%;辛德毕斯病毒2.6%;杜格贝病毒2.1%;登革2型病毒1.0%;西尼罗病毒0.9%;基孔肯雅病毒0.7%;内罗毕绵羊病病毒0.3%。未检测到克里米亚-刚果出血热病毒抗体的证据。数据表明,自1982年该地区发生登革热疫情以来,虫媒病毒活动较低,并首次揭示了肯尼亚人群中杜格贝病毒感染的证据。

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