sanofi-aventis, 46 Quai de la Rapée, Paris, France.
Diabetes Technol Ther. 2010 Jun;12 Suppl 1:S79-85. doi: 10.1089/dia.2009.0179.
Insulin is essential for the management of type 1 diabetes and is more commonly being used for the treatment of type 2 diabetes. Insulin pen devices were first introduced over 20 years ago and have evolved to provide significant practical advantages compared with the vial and syringe. Pen devices are now used by patients with diabetes worldwide, but there are marked geographical variations in the use of reusable and disposable pens. In some countries the vial and syringe is still the most popular method of administering insulin, whereas in other countries the use of reusable or disposable pens is more prevalent. Therefore, the aim of this review is to discuss the factors that seem to be involved in these differences, which include patient access to insulin, cost, and physician/patient awareness and preference. Inpatient use of insulin is also common, and the use of insulin pens could offer substantial benefits in this patient population, not only during the admission period but also after discharge from the hospital. However, the evidence base for inpatient use is still weak, and more studies are needed to investigate the use of insulin pens in this patient population.
胰岛素是 1 型糖尿病管理的基础,并且越来越多地用于治疗 2 型糖尿病。胰岛素笔设备在 20 多年前首次推出,与小瓶和注射器相比,已经进化为提供显著的实际优势。目前,世界各地的糖尿病患者都在使用胰岛素笔,但可重复使用和一次性笔的使用存在明显的地域差异。在一些国家,小瓶和注射器仍然是最受欢迎的胰岛素给药方法,而在其他国家,可重复使用或一次性笔的使用更为普遍。因此,本综述的目的是讨论似乎涉及这些差异的因素,这些因素包括患者获得胰岛素的机会、成本、医生/患者的意识和偏好。胰岛素的住院使用也很常见,胰岛素笔的使用可以为这部分患者群体带来实质性的益处,不仅在住院期间,而且在出院后也有帮助。然而,住院使用的证据基础仍然薄弱,需要更多的研究来调查胰岛素笔在这一患者群体中的使用情况。