Lingen Kathryn, Pikounis Talia, Bellini Natalie, Isaacs Diana
Close Concerns, San Francisco, California, USA.
University Hospitals, Cleveland, Ohio, USA.
Endocr Connect. 2023 Sep 27;12(11). doi: 10.1530/EC-23-0108. Print 2023 Nov 1.
Insulin administration remains vital to the treatment of diabetes and although there have been advances in insulin delivery, evidence suggests that many people with diabetes on insulin therapy have suboptimal glycemic management. Recent advancements in insulin administration techniques include connected insulin devices, such as connected insulin pens and pen caps. In this review, we provide an overview of the literature on the use of connected insulin pens and pen caps to further elucidate the clinical benefits and drawbacks of these devices. We discuss the development of these devices, outlining the characteristics of insulin pens and pen caps with regulatory approvals. These devices have different features that can ease the burden of diabetes management, including automatic recording of insulin dose information, tracking of insulin-on-board, bolus calculators, and missed dose alerts. Despite the advantages of connected pens and pen caps, a small percentage of insulin users are currently using these devices, due to many factors, including lack of health-care professional awareness, initial training for prescribers, and setup of the device. Overcoming these barriers and publishing more data demonstrating the glycemic outcomes associated with these systems could improve diabetes management for people living with diabetes. As health-care systems become increasingly digital, connected insulin pens have the potential to allow a data-driven approach to diabetes management for people who are not interested in, cannot afford, or do not have intensive insulin regimens that might warrant use of insulin pumps or automated insulin delivery systems.
胰岛素给药对于糖尿病治疗仍然至关重要,尽管胰岛素给药方式已有进展,但有证据表明,许多接受胰岛素治疗的糖尿病患者血糖管理并不理想。胰岛素给药技术的最新进展包括联网胰岛素设备,如联网胰岛素笔和笔帽。在本综述中,我们概述了关于使用联网胰岛素笔和笔帽的文献,以进一步阐明这些设备的临床益处和缺点。我们讨论了这些设备的发展情况,概述了获得监管批准的胰岛素笔和笔帽的特点。这些设备具有不同的功能,可以减轻糖尿病管理的负担,包括自动记录胰岛素剂量信息、追踪体内胰岛素量、大剂量计算器和漏服提醒。尽管联网笔和笔帽有诸多优点,但由于包括医疗保健专业人员缺乏认识、开处方者的初始培训以及设备设置等多种因素,目前只有一小部分胰岛素使用者在使用这些设备。克服这些障碍并发表更多证明这些系统与血糖结果相关的数据,可能会改善糖尿病患者的糖尿病管理。随着医疗保健系统日益数字化,联网胰岛素笔有可能为那些对强化胰岛素治疗方案不感兴趣、负担不起或不需要使用胰岛素泵或自动胰岛素输送系统的糖尿病患者提供一种数据驱动的糖尿病管理方法。