Microbiology Research Division, Bureau of Microbial Hazards, Food Directorate, Health Products and Food Branch, Health Canada, Sir FG Banting Research Centre, P.L. 2204E, Ottawa, ON, Canada.
Arch Virol. 2010 Jul;155(7):1127-37. doi: 10.1007/s00705-010-0700-6. Epub 2010 Jun 2.
Animal rotavirus (RoV) strains detected in Canadian swine and dairy cattle farms were characterized by sequence analysis of viral protein 4 (VP4), VP6, VP7 and non-structural protein 4 segments from 15 RoV strains. Some porcine strains were found to contain a mixture of segments typical of human and animal viruses. One strain represented a novel VP6 genotype "I14", G2-P[27]-I14. Other strains detected in porcine samples represented multiple different segment types. These results illustrate the active evolution of animal RoV strains and underline the need for surveillance of both animal and human strains in public health-monitoring programs.
对来自加拿大养猪场和奶牛场的动物轮状病毒（RoV）株进行了研究，通过对 15 株 RoV 株的病毒蛋白 4（VP4）、VP6、VP7 和非结构蛋白 4 段的序列分析进行了特征描述。一些猪源株被发现含有混合了人类和动物病毒片段的混合物。一株代表了一种新型的 VP6 基因型“ I14”，G2-P[27]-I14。在猪样本中检测到的其他菌株代表了多种不同的片段类型。这些结果说明了动物 RoV 株的活跃进化，并强调了在公共卫生监测计划中需要对动物和人类株进行监测。
