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德黑兰青少年代谢综合征表型的发生率和趋势:1998-2001 年至 2003-2006 年德黑兰血脂和血糖研究的结果。

Incidence and trend of a metabolic syndrome phenotype among Tehranian adolescents: findings from the Tehran Lipid and Glucose Study, 1998-2001 to 2003-2006.

机构信息

Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Science, Yazd, Iran.

出版信息

Diabetes Care. 2010 Sep;33(9):2110-2. doi: 10.2337/dc09-0023. Epub 2010 Jun 2.

Abstract

OBJECTIVE

To assess the incidence and trend of the metabolic syndrome phenotype in adolescents from the Tehran Lipid and Glucose Study during 3.6 years of follow-up.

RESEARCH DESIGN AND METHODS

A total of 932 adolescents, aged 10-19 years, who had complete data and returned for reassessment 3.6 years later were investigated.

RESULTS

Prevalence of metabolic syndrome at baseline and after 3.6 years was 7.4 and 6.7%, respectively, based on the Adult Treatment Panel (ATP) III definitions; 3.5 and 8.0%, respectively, based on the International Diabetes Federation (IDF) definitions; 4.1 and 9.4%, respectively, based on the American Heart Association (AHA) definitions; and 13.6 and 13.4%, respectively, based on the National Health and Nutrition Examination Survey (NHANES) definitions. Incidence rates were 5.2% (95% CI 3-6) based on ATP III, 6.8% (5-8) based on IDF, 8.3% (6-10) based on AHA, and 8.8% (6-10) based on NHANES definitions.

CONCLUSIONS

Incidence of metabolic syndrome is high in Tehranian adolescents.

摘要

目的

评估 3.6 年随访期间德黑兰血脂和血糖研究中青少年代谢综合征表型的发生率和趋势。

研究设计和方法

共调查了 932 名年龄在 10-19 岁之间、有完整数据且 3.6 年后返回重新评估的青少年。

结果

根据成人治疗小组 (ATP) III 定义,基线和 3.6 年后代谢综合征的患病率分别为 7.4%和 6.7%;根据国际糖尿病联合会 (IDF) 定义,分别为 3.5%和 8.0%;根据美国心脏协会 (AHA) 定义,分别为 4.1%和 9.4%;根据国家健康和营养检查调查 (NHANES) 定义,分别为 13.6%和 13.4%。根据 ATP III,发病率为 5.2%(95%CI 3-6),根据 IDF 为 6.8%(5-8),根据 AHA 为 8.3%(6-10),根据 NHANES 定义为 8.8%(6-10)。

结论

德黑兰青少年代谢综合征的发病率很高。

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