Suh D H, Lee H S, Kim S D, Cho K H, Kim K H, Park K C
Department of Dermatology, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
Pediatr Dermatol. 2000 Nov-Dec;17(6):466-8. doi: 10.1046/j.1525-1470.2000.01823.x.
Porokeratosis is a genodermatosis characterized by abnormal epidermal keratinization with the histologic finding of cornoid lamella. To date, five clinical variants have been identified. However, the coexistence of these variants in a single patient has been described only rarely. We report a 5-year-old girl with the simultaneous occurrence of porokeratotic lesions in linear and disseminated patterns. Linear lesions were detected at birth and the disseminated lesions developed at the age of 3 years. Histologically the lesions had cornoid lamella, which is typical of this condition.
汗孔角化症是一种遗传性皮肤病，其特征为表皮角质化异常，组织学表现为鸡眼样板层。迄今为止，已确定了五种临床变型。然而，这些变型在单一患者中共存的情况仅有极少报道。我们报告一名5岁女童，同时出现了线性和播散性汗孔角化病变。线性病变在出生时即被发现，播散性病变于3岁时出现。组织学检查显示病变有鸡眼样板层，这是该病的典型表现。
