通过体重指数衡量的新生儿肥胖可预测儿童期超重。
Newborn adiposity by body mass index predicts childhood overweight.
作者信息
Winter Jonathan David, Langenberg Patricia, Krugman Scott D
机构信息
Shenandoah Valley Family Practice Residency, 140 West 11th Street, Front Royal, VA 22630, USA.
出版信息
Clin Pediatr (Phila). 2010 Sep;49(9):866-70. doi: 10.1177/0009922810369698. Epub 2010 Jun 3.
OBJECTIVE
To evaluate the association between adiposity at birth and in infancy with overweight at age 5 years. This study hypothesizes that adiposity at birth as approximated by body mass index (BMI) predicts childhood fatness.
METHODS
Anthropomorphic data from birth to 5 years were used to calculate BMI percentiles. Multiple logistic regression assessed the association between BMI percentile > or =85% at 2 weeks and BMI percentile > or =85% at 6, 12, 36, and 60 months.
RESULTS
Elevated BMI at age 2 weeks > or =85th percentile was associated with significant increases in risk of overweight at 6, 12, 36, and 60 months of age. Infants with a BMI at age 2 weeks > or =85th percentile had an adjusted odds ratio of 3.42 (95% confidence interval [CI] = 1.79, 6.50) and an adjusted risk ratio of 2.12 (95% CI = 1.71, 2.61) of being overweight at 60 months of age.
CONCLUSIONS
Adiposity at birth as approximated by BMI is a significant predictor of overweight at 5 years.
目的
评估出生时及婴儿期肥胖与5岁时超重之间的关联。本研究假设，用体重指数（BMI）估算的出生时肥胖可预测儿童期肥胖。
方法
采用从出生到5岁的人体测量数据计算BMI百分位数。多元逻辑回归分析评估了2周龄时BMI百分位数≥85%与6、12、36和60月龄时BMI百分位数≥85%之间的关联。
结果
2周龄时BMI升高至≥第85百分位数与6、12、36和60月龄时超重风险显著增加相关。2周龄时BMI≥第85百分位数的婴儿在60月龄时超重的校正比值比为3.42（95%置信区间[CI]=1.79, 6.50），校正风险比为2.12（95% CI = 1.71, 2.61）。
结论
用BMI估算的出生时肥胖是5岁时超重的重要预测指标。
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