Medical Research Council Social and Public Health Sciences Unit, University of Glasgow, Glasgow.
BMJ. 2010 Jun 3;340:c2506. doi: 10.1136/bmj.c2506.
To explore associations between IQ measured in early adulthood and subsequent hospital admissions for attempted suicide and to explore the role of psychosis and examine associations of IQ with specific methods of attempted suicide.
Cohort study.
Sweden.
1 109 475 Swedish men with IQ measured in early adulthood followed up for an average 24 years.
Hospital admission for attempted suicide.
17 736 (1.6%) men had at least one hospital admission for attempted suicide by any means during follow-up. After adjustment for age and socioeconomic status, lower IQ scores were associated with an elevated risk of attempted suicide by any means (hazard ratio per standard deviation decrease in IQ=1.57, 95% confidence interval 1.54 to 1.60), with stepwise increases in risk across the full IQ range (P for trend<0.001). Similar associations were observed for all specific methods of attempted suicide. Separate analyses indicated that associations between IQ and attempted suicide were restricted to participants without psychosis and that IQ had no marked impact on risk of attempted suicide in those with psychosis.
Low IQ scores in early adulthood were associated with a subsequently increased risk of attempted suicide in men free from psychosis. A greater understanding of the mechanisms underlying these associations may provide opportunities and strategies for prevention.
探讨成年早期智商与随后自杀未遂住院之间的关联，并探讨精神病的作用，同时检验智商与特定自杀未遂方法之间的关联。
队列研究。
瑞典。
119475 名瑞典男性，在成年早期进行智商测试，平均随访 24 年。
自杀未遂住院。
在随访期间，17736（1.6%）名男性至少有一次通过任何手段自杀未遂的住院治疗。在调整年龄和社会经济地位后，较低的智商分数与任何手段自杀未遂的风险增加相关（每降低一个标准差智商的危害比=1.57，95%置信区间 1.54 至 1.60），在整个智商范围内风险呈逐步增加（趋势 P<0.001）。对于所有特定的自杀未遂方法，均观察到类似的关联。单独的分析表明，智商与自杀未遂之间的关联仅限于没有精神病的参与者，并且在患有精神病的参与者中，智商对自杀未遂风险没有明显影响。
成年早期较低的智商分数与无精神病男性随后自杀未遂风险的增加相关。更深入地了解这些关联的潜在机制可能为预防提供机会和策略。
