Fujii H, Nohira K, Yamamoto Y, Ikawa H, Ohura T
Appl Opt. 1987 Dec 15;26(24):5321-5. doi: 10.1364/AO.26.005321.
A new method is proposed to visualize the microcirculation map using a dynamic laser speckle effect. A skin surface is illuminated by He-Ne laser line spot and its image speckle is detected by a CCD array sensor. The erence between a pair of output data for successive scannings of the image speckles at the sensor plane was calculated and integrated for each pixel. The results were displayed in color graphics showing the spatial variation of the flow level in the area of interest.
提出了一种利用动态激光散斑效应可视化微循环图的新方法。用氦氖激光线光斑照射皮肤表面,并用电荷耦合器件(CCD)阵列传感器检测其图像散斑。计算并积分传感器平面上图像散斑连续扫描的一对输出数据之间的差异,对每个像素进行处理。结果以彩色图形显示,展示了感兴趣区域内血流水平的空间变化。