• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过激光散斑血流图可视化视网膜血流。

Visualisation of retinal blood flow by laser speckle flow-graphy.

作者信息

Fujii H

机构信息

Department of Computer Science and Electronics, Kyushu Institute of Technology, Fukuoka, Japan.

出版信息

Med Biol Eng Comput. 1994 May;32(3):302-4. doi: 10.1007/BF02512526.

DOI:10.1007/BF02512526
PMID:7934254
Abstract

A new method is demonstrated to visualise the microcirculation map of the human retina using a dynamic laser speckle effect. The retina is illuminated with a diode laser spot through a retinal camera, and its speckle image is detected by an area sensor. The output signal from the sensor is digitised, and the data for more than a hundred scannings of the speckle image are stored in a mass image memory. The difference between a pair of successive image data was calculated and integrated for each pixel. The results were displayed in colour graphics showing the spatial distribution of the blood flow in the retina.

摘要

一种利用动态激光散斑效应可视化人类视网膜微循环图的新方法得到了演示。通过视网膜相机用二极管激光光斑照射视网膜,并用面传感器检测其散斑图像。传感器的输出信号被数字化,散斑图像一百多次扫描的数据被存储在大容量图像存储器中。计算并整合每个像素的一对连续图像数据之间的差异。结果以彩色图形显示,展示了视网膜中血流的空间分布。

相似文献

1
Visualisation of retinal blood flow by laser speckle flow-graphy.通过激光散斑血流图可视化视网膜血流。
Med Biol Eng Comput. 1994 May;32(3):302-4. doi: 10.1007/BF02512526.
2
[An apparatus using the laser speckle phenomenon for non-invasive two-dimensional analysis of retinal microcirculation].
Nippon Ganka Gakkai Zasshi. 1994 Jan;98(1):47-54.
3
[Noninvasive two-dimensional analysis of retinal microcirculation using the laser speckle phenomenon--II. Comparison of results with those obtained with the microsphere technique].
Nippon Ganka Gakkai Zasshi. 1994 Feb;98(2):169-74.
4
Evaluation of blood flow by laser speckle image sensing. Part 1.通过激光散斑图像传感评估血流。第1部分。
Appl Opt. 1987 Dec 15;26(24):5321-5. doi: 10.1364/AO.26.005321.
5
Noncontact, two-dimensional measurement of retinal microcirculation using laser speckle phenomenon.利用激光散斑现象对视网膜微循环进行非接触式二维测量。
Invest Ophthalmol Vis Sci. 1994 Oct;35(11):3825-34.
6
[An apparatus using laser speckle phenomenon for noninvasive 2-dimensional analysis of microcirculation in the optic nerve head].
Nippon Ganka Gakkai Zasshi. 1993 Apr;97(4):501-8.
7
An application of laser speckle phenomenon for noninvasive two-dimensional evaluation of microcirculation in ocular fundus--a preliminary report.激光散斑现象在眼底微循环无创二维评估中的应用——初步报告
Jpn J Ophthalmol. 1993;37(2):178-86.
8
Time-course of changes in nicardipine effects on microcirculation in retina and optic nerve head in living rabbit eyes.尼卡地平对活体兔眼视网膜和视神经乳头微循环影响的时间变化过程。
Jpn J Ophthalmol. 1996;40(2):202-11.
9
[An apparatus using laser speckle phenomenon for noninvasive 2-dimensional analysis of choroidal microcirculation].
Nippon Ganka Gakkai Zasshi. 1993 May;97(5):602-9.
10
[In vivo measurement of ocular circulation with the laser speckle method--development of apparatus and application in ophthalmological research].[用激光散斑法进行眼循环的体内测量——仪器的研制及其在眼科研究中的应用]
Nippon Ganka Gakkai Zasshi. 1999 Dec;103(12):871-909.

引用本文的文献

1
Baseline Choroidal Blood Flow Imbalance as a Predictive Factor for Macular Edema Recurrence Secondary to Branch Retinal Vein Occlusion.基线脉络膜血流失衡作为视网膜分支静脉阻塞继发黄斑水肿复发的预测因素
Diagnostics (Basel). 2024 Oct 18;14(20):2328. doi: 10.3390/diagnostics14202328.
2
Evaluating the relationship between ocular blood flow and systemic organ blood flow in hemorrhagic shock using a rabbit model.评估兔失血性休克模型中眼血流与全身脏器血流的关系。
Sci Rep. 2024 Feb 14;14(1):3749. doi: 10.1038/s41598-024-54467-1.
3
Akimba Proliferative Diabetic Retinopathy Model: Understanding Molecular Mechanism and Drug Screening for the Progression of Diabetic Retinopathy.

本文引用的文献

1
Evaluation of blood flow by laser speckle image sensing. Part 1.通过激光散斑图像传感评估血流。第1部分。
Appl Opt. 1987 Dec 15;26(24):5321-5. doi: 10.1364/AO.26.005321.
2
Fundus camera based retinal LDV.基于眼底相机的视网膜激光散斑血流成像
Appl Opt. 1981 Jan 1;20(1):117-20. doi: 10.1364/AO.20.000117.
3
Blood flow observed by time-varying laser speckle.通过时变激光散斑观察到的血流。
阿克imba 增殖性糖尿病视网膜病变模型:了解糖尿病视网膜病变进展的分子机制和药物筛选。
Methods Mol Biol. 2023;2678:13-26. doi: 10.1007/978-1-0716-3255-0_2.
4
Improving blood flow in occluded veins to reduce anti-vascular endothelial growth factor injections for branch retinal vein occlusion.改善阻塞静脉的血流,以减少视网膜分支静脉阻塞的抗血管内皮生长因子注射。
Am J Ophthalmol Case Rep. 2023 Apr 23;30:101847. doi: 10.1016/j.ajoc.2023.101847. eCollection 2023 Jun.
5
Novel superpixel method to visualize fundus blood flow resistivity in healthy adults.新型超像素方法可用于可视化健康成年人眼底血流阻力。
Sci Rep. 2023 Apr 15;13(1):6171. doi: 10.1038/s41598-023-33450-2.
6
Relationship Between Retinal Microcirculation and Renal Function in Patients with Diabetes and Chronic Kidney Disease by Laser Speckle Flowgraphy.糖尿病合并慢性肾脏病患者视网膜微循环与肾功能的激光散斑血流图研究
Life (Basel). 2023 Feb 2;13(2):424. doi: 10.3390/life13020424.
7
Characteristics of laterality in the optic nerve head microcirculation obtained by laser speckle flowgraphy in healthy subjects.健康受试者的激光散斑血流图测量的视盘微循环偏侧性特征。
Graefes Arch Clin Exp Ophthalmol. 2022 Sep;260(9):2799-2805. doi: 10.1007/s00417-022-05631-8. Epub 2022 Mar 17.
8
Changes in pulse waveforms in response to intraocular pressure elevation determined by laser speckle flowgraphy in healthy subjects.健康受试者的激光散斑血流图测量眼压升高时的脉搏波变化。
BMC Ophthalmol. 2021 Aug 21;21(1):303. doi: 10.1186/s12886-021-02070-7.
9
Real-Time Evaluation of Regional Arterial Stiffening, Resistance, and Ocular Circulation During Systemic Administration of Adrenaline in White Rabbits.在白色兔子中,全身给予肾上腺素时,实时评估区域性动脉僵硬、阻力和眼部循环。
Transl Vis Sci Technol. 2021 Aug 2;10(9):11. doi: 10.1167/tvst.10.9.11.
10
Association of changes of retinal vessels diameter with ocular blood flow in eyes with diabetic retinopathy.糖尿病视网膜病变患者视网膜血管直径变化与眼血流的关系。
Sci Rep. 2021 Feb 25;11(1):4653. doi: 10.1038/s41598-021-84067-2.
Opt Lett. 1985 Mar 1;10(3):104-6. doi: 10.1364/ol.10.000104.
4
A new instrument for continuous measurement of tissue blood flow by light beating spectroscopy.
IEEE Trans Biomed Eng. 1980 Jan;27(1):12-9. doi: 10.1109/TBME.1980.326686.
5
Laser Doppler measurements of blood velocity in human retinal vessels.人体视网膜血管中血流速度的激光多普勒测量。
J Opt Soc Am. 1978 Apr;68(4):526-31. doi: 10.1364/josa.68.000526.