Division of Allergy and Clinical Immunology, St, Michael's Hospital, University of Toronto, Toronto, ON.
Allergy Asthma Clin Immunol. 2008 Dec 15;4(4):139-43. doi: 10.1186/1710-1492-4-4-139.
: Peanut allergies have been increasing in prevalence in most industrialized countries. Onset is typically in early childhood, with a trend towards earlier ages of presentation. The allergy is lifelong in most affected children, although 15-22% will outgrow their peanut allergy, usually before their teenage years. Manifestations of peanut allergy range from mild to severe, and risk factors predisposing to severe reactions are discussed. However, even in the absence of risk factors, peanut allergic individuals may still experience life-threatening anaphylactic reactions. Approaches to investigation and treatment, patterns of cross-reactivity and possible causes of rising prevalence are discussed.
花生过敏在大多数工业化国家的发病率一直在上升。发病通常在幼儿期,呈现出发病年龄提前的趋势。大多数受影响的儿童的过敏是终身的,尽管 15-22%的儿童会在青少年前摆脱花生过敏。花生过敏的表现从轻度到重度不等,讨论了导致严重反应的危险因素。然而,即使没有危险因素,花生过敏的个体仍可能发生危及生命的过敏反应。本文讨论了调查和治疗方法、交叉反应模式以及发病率上升的可能原因。