School of Health and Related Research (TAY, YY, JEB, AT) The University of Sheffield, Sheffield, United Kingdom.
Yorkshire and Humber Research Design Service (TAY) The University of Sheffield, Sheffield, United Kingdom.
Med Decis Making. 2011 Jan-Feb;31(1):195-210. doi: 10.1177/0272989X10364846. Epub 2010 Jun 4.
The majority of health-related quality-of-life instruments are not preference-based measures and so cannot be used within cost utility analysis. The Asthma Quality of Life Questionnaire (AQLQ) is one such instrument. The aim of this study was to develop a health state classification that was amenable to valuation from the AQLQ, this being the 1st stage in developing a condition-specific preference-based measure for asthma patients. Rasch models were applied to samples of responders to the AQLQ with the aim of selecting a number of items for a preference-based utility measure (AQL-5D). Selection of items for the evaluation survey was supported with classical psychometric criteria for item selection (feasibility, internal consistency, floor and ceiling effects, and responsiveness). Rasch analysis proved to be a useful tool in assisting in the initial process of selecting items from an existing health-related quality-of-life instrument in the construction of the AQL-5D. The method is recommended for use alongside classical psychometric testing to aid in the development of preference-based measures.
大多数与健康相关的生活质量工具都不是偏好测量工具，因此不能在成本效用分析中使用。哮喘生活质量问卷（AQLQ）就是这样一种工具。本研究的目的是开发一种适合于从 AQLQ 进行评估的健康状况分类，这是为哮喘患者开发特定于疾病的偏好测量工具的第 1 阶段。应用 Rasch 模型对 AQLQ 应答者的样本进行分析，目的是为基于偏好的效用测量（AQL-5D）选择一些项目。评估调查中项目的选择得到了经典心理测量标准（可行性、内部一致性、地板效应和天花板效应以及响应性）的支持。Rasch 分析被证明是一种有用的工具，可用于在构建 AQL-5D 时，从现有与健康相关的生活质量工具中选择项目的初始过程中提供帮助。该方法建议与经典心理测量测试一起使用，以帮助开发基于偏好的测量工具。
