Mathieu D, Rahmouni A, Anglade M C, Falise B, Beges C, Gheung P, Mollet J J, Vasile N
Department of Radiology, Hôpital Henri Mondor, Créteil, France.
Radiology. 1991 Jul;180(1):25-30. doi: 10.1148/radiology.180.1.2052704.
Twenty-two patients with 25 cases of focal nodular hyperplasia (FNH) proved with pathologic study were imaged with a TurboFLASH (fast low angle shot) sequence combined with bolus administration of gadolinium tetraazacyclododecanetetraacetic acid (DOTA), spin-echo (SE) T2-weighted sequences, and postcontrast T1-weighted sequences. FNH-liver signal-difference-to-noise ratios were quantified; the features of the central scar were qualitatively analyzed. On SE T2-weighted images, all FNHs were hyperintense; in two cases the central scar exhibited a high signal intensity associated with hypointense areas corresponding to fibrous tissue within the branches of the scar. Unenhanced TurboFLASH images always demonstrated the FNHs as hypointense and always depicted the central scar as a hypointense area within the lesion. After bolus injection, arterial enhancement of FNH was clearly seen, and in 10 of 25 lesions, enhancement within the scar was seen 40-80 seconds after injection. Both unenhanced and enhanced TurboFLASH sequences produced the best signal-difference-to-noise ratios in comparison with T2-weighted images.
对22例经病理研究证实为25个局灶性结节性增生（FNH）病例的患者，采用快速低角度激发（TurboFLASH）序列联合团注四氮杂环十二烷四乙酸钆（DOTA）、自旋回波（SE）T2加权序列以及增强后T1加权序列进行成像。对FNH-肝脏信号差与噪声比进行量化；对中央瘢痕的特征进行定性分析。在SE T2加权图像上，所有FNH均呈高信号；2例中央瘢痕表现为高信号强度，伴有与瘢痕分支内纤维组织相对应的低信号区。未增强的TurboFLASH图像总是显示FNH为低信号，并总是将中央瘢痕描绘为病变内的低信号区。团注后，可见FNH的动脉期强化，在25个病变中的10个病变中，注射后40-80秒可见瘢痕内强化。与T2加权图像相比，未增强和增强的TurboFLASH序列均产生了最佳的信号差与噪声比。
