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氚水产生的低能β辐射对3T3成纤维细胞形态的影响。

Effects of low energy beta-irradiation from tritiated water on the morphology of 3T3 fibroblasts.

作者信息

Somosy Z, Kubasova T, Kovács J, Köteles G J

机构信息

Frédéric Joliot-Curie, National Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary.

出版信息

Scanning Microsc. 1991 Mar;5(1):127-33; discussion 133-4.

PMID:2052918
Abstract

Cellular alterations of cultured 3T3 cells irradiated with beta-rays from tritiated water were studied by scanning and transmission electron microscopy. We observed decreased negative surface charges, vacuolization of rough endoplasmic reticulum and Golgi-complex, degeneration of mitochondria, increase of lysosomal activity and changes in distribution and amount of microfilaments in the irradiated cells, that parallelled changes in cell shape.

摘要

用氚水的β射线照射培养的3T3细胞,通过扫描电子显微镜和透射电子显微镜研究其细胞变化。我们观察到受照射细胞的表面负电荷减少、粗面内质网和高尔基体空泡化、线粒体退化、溶酶体活性增加以及微丝的分布和数量发生变化,这些变化与细胞形态的改变平行。

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