糖尿病患者中高密度脂蛋白和低密度脂蛋白与血管疾病患病率的关系
High-density and low-density lipoproteins and prevalence of vascular disease in diabetes mellitus.
作者信息
Reckless J P, Betteridge D J, Wu P, Payne B, Galton D J
出版信息
Br Med J. 1978 Apr 8;1(6117):883-6. doi: 10.1136/bmj.1.6117.883.
Abstract
The prevalence of vascular disease among 154 diabetic patients was analysed in relation to the serum concentrations of individual lipoproteins. Overal the presence of vascular disease (59 cases) was positively associated with serum cholesterol and low-density-lipoprotein cholesterol but negatively associated with high-density-lipoprotein (HDL) cholesterol. The negative relation between HDL and vascular disease was not observed in all subgroups of diabetics. We conclude that there may be no overriding association between HDL and vascular disease in diabetics as proposed for some non-diabetic populations.
摘要
分析了154例糖尿病患者血管疾病的患病率与个体脂蛋白血清浓度之间的关系。总体而言，血管疾病（59例）的存在与血清胆固醇和低密度脂蛋白胆固醇呈正相关，但与高密度脂蛋白（HDL）胆固醇呈负相关。在糖尿病患者的所有亚组中均未观察到HDL与血管疾病之间的负相关关系。我们得出结论，对于糖尿病患者而言，HDL与血管疾病之间可能不存在如某些非糖尿病人群中所提出的那种压倒性关联。
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本文引用的文献
1
Arteriosclerotic heart disease in diabetes mellitus; a clinical study of 383 patients.
Am J Med. 1955 Mar;18(3):438-47. doi: 10.1016/0002-9343(55)90224-2.
2
Some effects of administering sodium fluoride to patients with Paget's disease.给佩吉特氏病患者施用氟化钠的一些效果。
Lancet. 1962 Dec 8;2(7267):1188-9. doi: 10.1016/s0140-6736(62)90958-3.
3
The significance of blood lipid alterations in diabetes mellitus.糖尿病中血脂改变的意义。
Diabetes. 1963 May-Jun;12:208-12. doi: 10.2337/diab.12.3.208.
4
The fluorometric assay of triglyceride by a semiautomated method.甘油三酯的半自动化荧光测定法。
Anal Biochem. 1968 Oct 24;25(1):246-51. doi: 10.1016/0003-2697(68)90097-3.
5
Myocardial infarction and carbohydrate metabolism.
Geriatrics. 1968 Jan;23(1):158-60.
6
Hypertriglyceridemia, diabetes mellitus, and coronary vessel disease.
Arch Intern Med. 1969 Mar;123(3):220-8.
7
Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study.弗雷明汉姆人群中糖尿病患者的发病率和死亡率。十六年随访研究。
Diabetes. 1974 Feb;23(2):105-11. doi: 10.2337/diab.23.2.105.
8
Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions.通过用聚阴离子沉淀从人血清中分离脂蛋白的快速方法。
J Lipid Res. 1970 Nov;11(6):583-95.
9
Interaction between high density and low density lipoproteins uptake and degradation by cultured human fibroblasts.培养的人成纤维细胞对高密度脂蛋白和低密度脂蛋白的摄取与降解之间的相互作用。
J Clin Invest. 1977 Jul;60(1):78-88. doi: 10.1172/JCI108772.
10
High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study.高密度脂蛋白作为冠心病的保护因素。弗明汉姆研究。
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