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The role of penicillin amidases in nature and in industry.

作者信息

Valle F, Balbás P, Merino E, Bolivar F

机构信息

Centro de Investigación sobre, Ingeniería Genética y Biotecnologia, Universidad Nacional Autónoma de México.

出版信息

Trends Biochem Sci. 1991 Jan;16(1):36-40. doi: 10.1016/0968-0004(91)90014-m.

DOI:10.1016/0968-0004(91)90014-m
PMID:2053136
Abstract

Penicillin amidase (PA) is the enzyme used commercially for the production of semisynthetic penicillins. During the past decade, a detailed picture of the structure and regulation of the gene encoding this enzyme has emerged, revealing a variety of interesting features that are unique among microorganisms. Clues to the biological role of this enzyme have been provided, as well as new strategies for the commercial production and utilization of PA.

摘要

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