Ninković M, Ranković B, Plavec G
Vojnosanit Pregl. 1991 Jan-Feb;48(1):19-22.
In 105 patients with chronic obstructive pulmonary disease the bronchodilator response to salbutamol aerosol (ventolin) has been studied. According to the initial values of FEV1 (forced expiratory volume in one second) the patients were divided into four groups. Patients with bronchitis in the first group had the initial FEV1 between 600 and 1000 ml and in the second group between 100 and 2000 ml, while asthmatics in the third group had between 100 and 2000 ml and in the fourth group more than 2000 ml. The largest bronchodilator response was obtained in the groups of asthmatics (mean FEV1 increase was 473 +/- 258 ml in the third group and 609 +/- 334 ml in the fourth group). For evaluation of reversibility of obstruction of the respiratory ways after bronchodilatator tests and for better differentiation of chronic obstructive bronchitis and asthma the criteria have been proposed depending on the initial FEV1 values.
对105例慢性阻塞性肺疾病患者的沙丁胺醇气雾剂(万托林)支气管扩张反应进行了研究。根据第一秒用力呼气量(FEV1)的初始值,将患者分为四组。第一组患支气管炎的患者FEV1初始值在600至1000毫升之间,第二组在100至2000毫升之间,而第三组哮喘患者的FEV1在100至2000毫升之间,第四组超过2000毫升。哮喘组获得的支气管扩张反应最大(第三组FEV1平均增加473±258毫升,第四组为609±334毫升)。为了评估支气管扩张试验后呼吸道阻塞的可逆性以及更好地区分慢性阻塞性支气管炎和哮喘,根据FEV1初始值提出了相应标准。