Poison Control and Drug Information Center, An-Najah National University, Nablus, Palestine.
Basic Clin Pharmacol Toxicol. 2010 Nov;107(5):914-8. doi: 10.1111/j.1742-7843.2010.00601.x.
The objectives were to (i) analyse the pattern of poisoning and (ii) study gender distribution and management protocol of poisoning in patients diagnosed with acute poisoning. A retrospective analysis of cases diagnosed with acute poisoning and admitted to the emergency department of Al-Wattani governmental hospital during the year of 2008 was carried out. Data from patients' medical files were collected and then analysed using Statistical Package for Social Sciences (spss; SPSS Inc., Chicago, IL, USA), version 16. There were 674 cases diagnosed with acute poisoning in 2008 which accounted for 1.5% of the total admission to the hospital. The mean age of the cases was 21.8 ± 18.1 years. Approximately, 58% of poisoning cases occurred at home. Male to female ratio was 1.5:1. The maximum number of poisoning occurred during summer season. Poisoning cases were maximum in the age category >18 years. More than half (92%) of the cases were of unintentional type of poisoning. Unintentional poisoning was significantly more common among males (61.3%; p < 0.01), while intentional was more common among females (64.8%; p < 0.001). The causative agents encountered were mainly biological agents (77.4%), pharmaceuticals (11.6%), and other chemicals (10.9%). The most common route of poisoning was through stings (72.3%), followed by oral ingestion (23.5%) and inhalation (3.4%). The majority (91.1%) of cases did not undergo any decontamination methods. Of those who had decontamination procedure, gastric lavage was the most commonly used. This is the first study in Palestine that presents data on the pattern of acute poisoning. Awareness campaigns should be held about potentially toxic materials in the region, and methods of poison prevention should be spread among the public.
(i) 分析中毒模式，(ii) 研究性别分布和诊断为急性中毒患者的中毒管理方案。对 2008 年期间在 Al-Wattani 政府医院急诊科诊断为急性中毒并入院的病例进行回顾性分析。从患者病历中收集数据，然后使用统计软件包（spss; SPSS Inc.，芝加哥，IL，美国），版本 16 进行分析。2008 年共诊断出 674 例急性中毒病例，占医院总入院人数的 1.5%。病例的平均年龄为 21.8 ± 18.1 岁。大约 58%的中毒病例发生在家庭中。男女比例为 1.5:1。中毒发生最多的季节是夏季。中毒病例在 >18 岁年龄组最多。超过一半（92%）的病例为非故意中毒类型。非故意中毒在男性中更为常见（61.3%；p < 0.01），而故意中毒在女性中更为常见（64.8%；p < 0.001）。遇到的致病剂主要是生物制剂（77.4%）、药物（11.6%）和其他化学品（10.9%）。最常见的中毒途径是刺伤（72.3%），其次是口服摄入（23.5%）和吸入（3.4%）。大多数（91.1%）病例未进行任何清除方法。在进行了清除程序的病例中，洗胃是最常用的方法。这是巴勒斯坦的第一项研究，提供了关于急性中毒模式的数据。应在该地区开展有关潜在有毒物质的宣传活动，并向公众传播预防中毒的方法。
