Yong Loo Lin School of Medicine, National University of Singapore and Gleneagles Hospital, Singapore.
J Neurogastroenterol Motil. 2010 Jan;16(1):30-4. doi: 10.5056/jnm.2010.16.1.30. Epub 2010 Jan 31.
This review presents studies that support an inflammation-immunological model for the pathogenesis of post-infectious irritable bowel syndrome (IBS), and highlights recent studies that support a similar disease model in non-post-infectious IBS, in particular, diarrhoea-predominant IBS, as well as in post-infectious functional dyspepsia. These recent studies are highlighted to demonstrate that one line of research in functional gastrointestinal disorders has moved away from the old psychosomatic concepts. It is hoped that this will encourage future students of this field to explore the role of immunological events.
这篇综述介绍了支持感染后肠易激综合征(IBS)发病机制的炎症-免疫模型的研究,并强调了最近支持非感染后 IBS、特别是腹泻型 IBS 以及感染后功能性消化不良中类似疾病模型的研究。这些最近的研究被强调是为了表明功能性胃肠疾病的一条研究路线已经远离了旧的身心概念。希望这将鼓励该领域的未来学者探索免疫事件的作用。