Gastrointestinal Motility Research Unit, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
J Neurogastroenterol Motil. 2010 Apr;16(2):131-8. doi: 10.5056/jnm.2010.16.2.131. Epub 2010 Apr 27.
Rice- and chili-containing foods are common in Asia. Studies suggest that rice is completely absorbed in the small bowel, produces little intestinal gas and has a low allergenicity. Several clinical studies have demonstrated that rice-based meals are well tolerated and may improve gastrointestinal symptoms in functional gastrointestinal disorders (FGID). Chili is a spicy ingredient commonly use throughout Asia. The active component of chili is capsaicin. Capsaicin can mediate a painful, burning sensation in the human gut via the transient receptor potential vanilloid-1 (TRPV1). Recently, the TRPV1 expressing sensory fibers have been reported to increase in the gastrointestinal tract of patients with FGID and visceral hypersensitivity. Acute exposure to capsaicin or chili can aggravate abdominal pain and burning in dyspepsia and IBS patients. Whereas, chronic ingestion of natural capsaicin agonist or chili has been shown to decrease dyspeptic and gastroesophageal reflux disease (GERD) symptoms. The high prevalence of spicy food in Asia may modify gastrointestinal burning symptoms in patients with FGID. Studies in Asia demonstrated a low prevalence of heartburn symptoms in GERD patients in several Asian countries. In conclusion rice is well tolerated and should be advocated as the carbohydrate source of choice for patients with FGID. Although, acute chili ingestion can aggravate abdominal pain and burning symptoms in FGID, chronic ingestion of chili was found to improve functional dyspepsia and GERD symptoms in small randomized, controlled studies.
含大米和辣椒的食物在亚洲很常见。研究表明,大米在小肠中被完全吸收,产生的肠道气体很少,且致敏性低。几项临床研究表明,以大米为主的膳食耐受性良好,并可能改善功能性胃肠病(FGID)的胃肠道症状。辣椒是亚洲常用的一种辛辣成分。辣椒的活性成分是辣椒素。辣椒素可通过瞬时受体电位香草酸 1 型(TRPV1)在人体肠道中介导疼痛和烧灼感。最近,有报道称 FGID 和内脏高敏患者的胃肠道中 TRPV1 表达感觉纤维增加。辣椒素或辣椒的急性暴露可加重消化不良和 IBS 患者的腹痛和烧灼感。然而,天然辣椒素激动剂或辣椒的慢性摄入已被证明可减轻消化不良和胃食管反流病(GERD)的症状。亚洲辛辣食物的高流行率可能会改变 FGID 患者的胃肠道烧灼感症状。亚洲的研究表明,在几个亚洲国家,GERD 患者的烧心症状患病率较低。总之,大米耐受性良好,应提倡作为 FGID 患者的首选碳水化合物来源。虽然辣椒素的急性摄入会加重 FGID 患者的腹痛和烧灼感症状,但在小型随机对照研究中发现,辣椒素的慢性摄入可改善功能性消化不良和 GERD 症状。