Hepatobiliary and Oncologic Surgery, Roger Williams Medical Center, Providence, RI, USA.
J Gastrointest Surg. 2010 Aug;14(8):1298-303. doi: 10.1007/s11605-010-1242-7. Epub 2010 Jun 10.
Various techniques have been described to achieve definitive resolution of complex acute pancreatitis associated pseudocysts (PACs). Many of these strategies, inclusive of open, minimally invasive, and radiological procedures, are hampered by high recurrence or failed resolution, particularly for PAC near the pancreatic head. The present series describes a multimodal strategy combining a minilaparotomy for anterior gastrostomy for the creation of a stapled posterior cystogastrostomy, placement of an 8F secured silastic tube for intentional formation of a cystogastric fistula tract in combination with gastric drainage, and postduodenal enteral alimentation.
Using a prospectively maintained hepatobiliary database, patients with complex PAC undergoing the above procedures were identified. PAC location, postoperative length of stay (LOS), and time to start enteral feeding were identified. PAC were assessed by computed tomography (CT) scan prior to operation, 1 month after drainage, and patients with PAC resolution were started on oral diet, with the fistula silastic tube kept in place for an additional month.
Over the interval 2003 to 2008, 19 patients were managed with the stated strategy. PACs were located at the pancreatic body/tail in 12 patients, and 7 patients had PAC at the level of the pancreatic head/neck area. In this cohort, prior to surgical drainage, 17/19 patients had undergone failed endoscopic retrograde cholangiopancreatography (ERCP) with decompressive stent placement and 13/19 had a failed percutaneous PAC drainage. There was no perioperative mortality after open surgical drainage. All patients started on jejunal tube feeding 24 h after surgical procedure. Median postoperative LOS was 7 days (4-13). At 1 month, 16/19 (84%) of patients showed complete resolution of the PAC on CT scan and were started on oral diet; 3/19 required additional month for complete resolution. After a mean follow-up of 31 months, there was no PAC recurrences in any of these patients demonstrated on follow-up.
The described strategy is safe, efficient, and allows early restoration of enteral feeding with early hospital discharge. High resolution rates and absence of PAC recurrences in this series supports this approach for complex PAC.
为了彻底解决与急性胰腺炎相关的复杂假性囊肿(PAC),已经有多种技术被描述出来。这些策略包括开放性、微创性和放射性程序,但都因高复发率或未能解决而受到阻碍,特别是对于靠近胰头的 PAC。本系列描述了一种多模式策略,包括小开腹前胃造口术以建立吻合的胃后囊造口术,放置 8F 固定硅酮管以有意形成囊胃瘘管,并结合胃引流,以及十二指肠后肠内营养。
使用前瞻性维护的肝胆数据库,确定了接受上述手术的复杂 PAC 患者。确定 PAC 的位置、术后住院时间(LOS)和开始肠内喂养的时间。在手术前、引流后 1 个月以及 PAC 得到解决的患者进行计算机断层扫描(CT)扫描评估,让患者开始口服饮食,瘘管硅酮管保留一个月。
在 2003 年至 2008 年期间,19 名患者接受了所述策略的治疗。12 名患者的 PAC 位于胰体/尾部,7 名患者的 PAC 位于胰头/颈部区域。在这组患者中,在手术引流之前,17/19 名患者曾接受过失败的内镜逆行胰胆管造影(ERCP)和减压支架放置,13/19 名患者曾接受过失败的经皮 PAC 引流。开放性手术引流后无围手术期死亡。所有患者在手术后 24 小时开始进行空肠管喂养。中位术后 LOS 为 7 天(4-13 天)。在 1 个月时,16/19(84%)名患者的 PAC 在 CT 扫描上完全得到解决,并开始口服饮食;3/19 名患者需要额外一个月才能完全解决。在平均 31 个月的随访中,在这些患者中没有任何 PAC 复发。
所描述的策略是安全、有效、能够早期恢复肠内喂养并尽早出院。本系列中高分辨率率和 PAC 无复发支持这种复杂 PAC 的方法。