与儿童硬斑病、系统性硬化症以及系统性红斑狼疮/硬皮病重叠综合征相关的鱼鳞病样皮肤改变。

Ichthyotic-appearing skin changes associated with childhood morphea, systemic sclerosis, and systemic lupus erythematosus/scleroderma overlap.

作者信息

Williams Christy M, Storm Craig A, Burns Christopher, Rigby William, Dinulos James G H

机构信息

Section of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA.

出版信息

Pediatr Dermatol. 2010 Mar-Apr;27(2):170-3. doi: 10.1111/j.1525-1470.2010.01108.x.

DOI:10.1111/j.1525-1470.2010.01108.x

PMID:20537069

Abstract

Ichthyotic-appearing skin changes have been associated with autoimmune disorders, including systemic lupus erythematosus and systemic sclerosis in adults. We report three children with ichthyotic-appearing skin changes that may be an early feature reflecting underlying dermal sclerosis. Detection of these subtle skin changes may be predictive of more widespread cutaneous involvement, ultimately prompting earlier treatment.

摘要

鱼鳞样皮肤改变与自身免疫性疾病有关，包括成人的系统性红斑狼疮和系统性硬化症。我们报告了三名患有鱼鳞样皮肤改变的儿童，这些改变可能是潜在真皮硬化的早期特征。检测到这些细微的皮肤改变可能预示着更广泛的皮肤受累，最终促使更早进行治疗。