Isler H, Bauen A, Hubler M, Oberholzer M
Solco Basle Ltd, Department of Pharmacology, Birsfelden, Switzerland.
Burns. 1991 Apr;17(2):99-103. doi: 10.1016/0305-4179(91)90131-y.
Morphological changes during soft-tissue repair are prime indicators of the processes involved in wound healing. A method has been developed to quantify such changes and applied for assessing the healing of partial thickness dermatome wounds treated either with Solcoseryl jelly or the matching vehicle. After 4 days of treatment, the active-treated wounds had already reached the reparative phase, whereas the vehicle-treated wounds were still in the proliferative phase. Furthermore, wound re-epithelialization was significantly improved under active treatment (P less than 0.005).
软组织修复过程中的形态学变化是伤口愈合相关进程的主要指标。现已开发出一种方法来量化此类变化，并将其应用于评估使用素高捷疗软膏或对照赋形剂治疗的断层皮片部分厚度伤口的愈合情况。治疗4天后，积极治疗组的伤口已进入修复期，而赋形剂治疗组的伤口仍处于增殖期。此外，积极治疗可显著促进伤口再上皮化（P<0.005）。
