Rudowski W, Kluciński W, Kopeć J, Sitarska E, Brudzyńska-Charewicz S, Nasiłowski W, Rusiniak L
Burns Incl Therm Inj. 1984 Jun;10(5):363-7. doi: 10.1016/s0305-4179(84)80010-8.
Investigations were carried out in three groups of rats (10 rats per group) sustaining partial skin thickness burns covering 2.2 per cent of body surface area. Thirty minutes after burning animals received: Group I, 1 ml Solcoseryl, IP; Group II, 1 ml normal saline, IP; Group III, no treatment (controls). Two hours after burning tissue respiration and the tissue concentrations of potassium, magnesium, calcium and sodium ions were measured in biopsies from the burn wounds. It was found that early post-burn administration of Solcoseryl significantly inhibited the secondary destructive processes and accelerated the regeneration of damaged tissue.
对三组大鼠（每组10只）进行了研究，这些大鼠遭受了占体表面积2.2%的部分皮肤厚度烧伤。烧伤后30分钟，动物接受：第一组，腹腔注射1毫升素高捷疗；第二组，腹腔注射1毫升生理盐水；第三组，不治疗（对照组）。烧伤后两小时，测量烧伤创面活检组织中的组织呼吸以及钾、镁、钙和钠离子的组织浓度。结果发现，烧伤后早期给予素高捷疗可显著抑制继发性破坏过程，并加速受损组织的再生。
