Isler H, Bauen A, Baschong W
Solco Basle AG, Pharmacology Department, Birsfelden, Switzerland.
Burns. 1991 Apr;17(2):93-7. doi: 10.1016/0305-4179(91)90130-9.
The utility of the protein-free haemodialysate Solcoseryl (HD) in the treatment of chronic skin ulcers and minor burns is well documented (Haigis et al., 1985). In this study the effects of HD ointment and HD gel on the healing of standardized deep partial thickness burns were investigated in rats. Treatment with HD-containing topical agents significantly reduced healing time (P less than or equal to 0.01) in comparison with non-treated controls; HD ointment and HD gel reduced relative healing rates by 20 per cent and 15 per cent respectively. Macroscopic and histological findings indicate that the effects of HD start in the early phase of the healing process (inflammatory/exudative), and that the entire healing process is improved.
无蛋白血液透析液Solcoseryl（HD）在治疗慢性皮肤溃疡和轻度烧伤方面的效用已有充分记录（海吉斯等人，1985年）。在本研究中，对大鼠标准化深Ⅱ度烧伤愈合过程中HD软膏和HD凝胶的作用进行了研究。与未治疗的对照组相比，含HD的局部用药显著缩短了愈合时间（P≤0.01）；HD软膏和HD凝胶分别使相对愈合率降低了20%和15%。宏观和组织学研究结果表明，HD的作用始于愈合过程的早期阶段（炎症/渗出期），并且整个愈合过程都得到了改善。
