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益生菌:防御系统的有益因素。

Probiotics: beneficial factors of the defence system.

机构信息

Danone Research, RD 128, F-91767 Palaiseau Cedex, France.

出版信息

Proc Nutr Soc. 2010 Aug;69(3):429-33. doi: 10.1017/S0029665110001692. Epub 2010 Jun 14.

Abstract

Probiotics, defined as living micro-organisms that provide a health benefit to the host when ingested in adequate amounts, have been used traditionally as food components to help the body to recover from diarrhoea. They are commonly ingested as part of fermented foods, mostly in fresh fermented dairy products. They can interact with the host through different components of the gut defence systems. There is mounting clinical evidence that some probiotics, but not all, help the defence of the host as demonstrated by either a shorter duration of infections or a decrease in the host's susceptibility to pathogens. Different components of the gut barrier can be involved in the strengthening of the body's defences: the gut microbiota, the gut epithelial barrier and the immune system. Many studies have been conducted in normal free-living subjects or in subjects during common infections like the common cold and show that some probiotic-containing foods can improve the functioning of or strengthen the body's defence. Specific probiotic foods can be included in the usual balanced diet of consumers to help them to better cope with the daily challenges of their environment.

摘要

益生菌被定义为摄入足够量时可以为宿主提供健康益处的活菌,传统上被用作食品成分,以帮助身体从腹泻中恢复。它们通常作为发酵食品的一部分摄入,主要是在新鲜发酵的乳制品中。它们可以通过肠道防御系统的不同成分与宿主相互作用。越来越多的临床证据表明,一些益生菌,而不是全部,有助于宿主的防御,这表现在感染持续时间缩短或宿主对病原体的易感性降低。肠道屏障的不同成分可能参与增强身体的防御能力:肠道微生物群、肠道上皮屏障和免疫系统。许多研究已经在正常的自由生活的受试者或在普通感染如普通感冒的受试者中进行,表明一些含有益生菌的食物可以改善或增强身体的防御功能。特定的益生菌食品可以包含在消费者的日常均衡饮食中,以帮助他们更好地应对日常环境的挑战。

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